Prospective nested case–control study of feature genes related to leukemic evolution of myelodysplastic syndrome

We established a nested case–control study cohort of myelodysplastic syndrome patients ( n  = 435). And 41 patients had conditions progressing to leukemia (case group = 41), 342 patients had no leukemic transformation (control group = 342), and 52 patients died. Bone marrow mononuclear cell of the p...

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