Gastroretentive Gabapentin (G-GR) Formulation Reduces Intensity of Pain Associated With Postherpetic Neuralgia (PHN)

OBJECTIVE:To evaluate the safety and efficacy of a once-daily gastroretentive formulation of gabapentin (G-GR; 1800 mg). METHODS:This was an 11-week, double-blind, randomized, placebo-controlled Phase 3 clinical trial in patients with postherpetic neuralgia. Patients underwent a 2-week dose titratio...

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Veröffentlicht in:	The Clinical journal of pain 2013-04, Vol.29 (4), p.281-288
Hauptverfasser:	Sang, Christine N, Sathyanarayana, Rekha, Sweeney, Michael
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Amines - administration & dosage Amines - therapeutic use Analgesics - administration & dosage Analgesics - therapeutic use Cyclohexanecarboxylic Acids - administration & dosage Cyclohexanecarboxylic Acids - therapeutic use Delayed-Action Preparations Double-Blind Method Drug Administration Schedule Female gamma-Aminobutyric Acid - administration & dosage gamma-Aminobutyric Acid - therapeutic use Humans Male Middle Aged Neuralgia, Postherpetic - drug therapy Pain Measurement Severity of Illness Index Treatment Outcome
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