The procyanidin trimer C1 inhibits LPS-induced MAPK and NF-κB signaling through TLR4 in macrophages

Natural products and dietary components rich in polyphenols have been shown to reduce inflammation; however, the molecular mechanisms underlying this anti-inflammatory activity are not completely characterized, and many features remain to be elucidated. This research was carried out to clarify the p...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	International immunopharmacology 2013-02, Vol.15 (2), p.450-456
Hauptverfasser:	Byun, Eui-Baek, Sung, Nak-Yun, Byun, Eui-Hong, Song, Du-Sup, Kim, Jae-Kyung, Park, Jong-Heum, Song, Beom-Seok, Park, Sang-Hyun, Lee, Ju-Woon, Byun, Myung-Woo, Kim, Jae-Hun
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-inflammation Anti-Inflammatory Agents, Non-Steroidal - pharmacology Antigens, CD - metabolism Biflavonoids - pharmacology Catechin - pharmacology Cell Line Cyclooxygenase 2 - metabolism Cytokines Dinoprostone - metabolism Inflammation - drug therapy Lipopolysaccharide Lipopolysaccharides - immunology Macrophages - drug effects Macrophages - immunology MAP Kinase Signaling System - drug effects MAP Kinase Signaling System - genetics Mice Mitogen-activated protein kinases NF-kappa B - metabolism Nitric Oxide - metabolism Nuclear factor-κB Proanthocyanidins - pharmacology Procyanidin C1 Toll-Like Receptor 4 - immunology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!