Synthesis, characterization and biological screening of 5-substituted-1,3,4-oxadiazole-2yl-N-(2-methoxy-5-chlorophenyl)-2-sulfanyl acetamide

In the current study, a series of 5-substituted-1,3,4-oxadiazole-2yl-N-(2-methoxy-5-chlorophenyl)-2-sulfanyl acetamide was synthesized by converting variously substituted/unsubstituted aromatic organic acids successively into the corresponding esters, hydrazides and then 5-substituted-1,3,4-oxadiazo...

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Veröffentlicht in:	Pakistan journal of pharmaceutical sciences 2013-03, Vol.26 (2), p.345-352
Hauptverfasser:	Rehman, Azizur, Fatima, Ambreen, Abbas, Nadia, Abbasi, Muhammad Athar, Khan, Khalid Mohammed, Ashraf, Muhammad, Ahmad, Irshad, Ejaz, Syeda Abida
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetamides - chemical synthesis Acetamides - pharmacology Acetylcholinesterase - metabolism Amides Butyrylcholinesterase - metabolism Chemical properties Chemical synthesis Cholinesterase Inhibitors - chemical synthesis Cholinesterase Inhibitors - pharmacology Composition Identification and classification Lipoxygenase - metabolism Lipoxygenase Inhibitors - chemical synthesis Lipoxygenase Inhibitors - pharmacology Magnetic Resonance Spectroscopy Mass Spectrometry Medical screening Methods Molecular Structure Oxadiazoles - chemical synthesis Oxadiazoles - pharmacology Pharmaceutical chemistry Production processes Spectrophotometry, Infrared Structure-Activity Relationship
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