Synthesis and in vitro antibacterial activity of quinolone/naphthyridone derivatives containing 3-alkoxyimino-4-(methyl)aminopiperidine scaffolds

A series of 7-[3-alkoxyimino-4-(methyl)aminopiperidin-1-yl]quinolone/naphthyridone derivatives were synthesized. Compounds 19a2, 19a4 and 19a5 were found to show strong antibacterial activity against all of the tested 15 Gram-positive strains. We report herein the synthesis of a series of 7-[3-alkox...

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