A Liquid Chromatographic Method for Quantifying Unbound Micafungin in Human Plasma and the Relationship between the Concentrations of Unbound and Total Micafungin in Plasma

This report describes a modified method for the quantitative determination of unbound micafungin (MCFG) in human plasma that is unrelated to chemical methods currently in use, and the relationship between the concentration of unbound and total MCFG in plasma of the patients. The mobile phase consist...

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Veröffentlicht in:	YAKUGAKU ZASSHI 2013, Vol.133(3), pp.397-404
Hauptverfasser:	Noda, Kumiko, Yokoyama, Toshinori, Akiyama, Yasushi, Tadano, Koji
Format:	Artikel
Sprache:	eng ; jpn
Schlagworte:	Aged Aged, 80 and over Chromatography, High Pressure Liquid Echinocandins - blood Female human plasma Humans Lipopeptides - blood Male Micafungin Serum Albumin - analysis therapeutic drug monitoring unbound drug concentration
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