Chondromodulin-I derived from the inner meniscus prevents endothelial cell proliferation

The meniscus is a fibrocartilaginous tissue that plays an important role in controlling complex biomechanics of the knee. A perimeniscal capillary plexus supplies the outer meniscus, whereas the inner meniscus is composed of avascular tissue. Anti‐angiogenic molecules, such as chondromodulin‐I (ChM‐...

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Veröffentlicht in:	Journal of orthopaedic research 2013-04, Vol.31 (4), p.538-543
Hauptverfasser:	Fujii, Masataka, Furumatsu, Takayuki, Yokoyama, Yusuke, Kanazawa, Tomoko, Kajiki, Yuya, Abe, Nobuhiro, Ozaki, Toshifumi
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged angiogenesis Arthroplasty, Replacement, Knee Cell Proliferation - drug effects Cells, Cultured chondromodulin-I endostatin Endostatins - biosynthesis Endothelial Cells - drug effects Humans Intercellular Signaling Peptides and Proteins - biosynthesis Intercellular Signaling Peptides and Proteins - physiology Membrane Proteins - biosynthesis Membrane Proteins - physiology Menisci, Tibial - metabolism meniscus
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