Achyranthes bidentata polysaccharides induce chondrocyte proliferation via the promotion of the G1/S cell cycle transition

Achyranthes bidentata polysaccharides (ABPS) are the major bioactive constituents of Radix Achyranthes bidentata (AB), which has been widely used in traditional Chinese medicine for the treatment of osteoarthritis. However, the molecular mechanisms behind the therapeutic effect of ABPS remain unclea...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Molecular medicine reports 2013-03, Vol.7 (3), p.935-940
Hauptverfasser:	YU, FANGRONG, LI, XIHAI, CAI, LIANGLIANG, LI, HUITING, CHEN, JIASHOU, WONG, XIAPING, XU, HUIFENG, ZHENG, CHUNSONG, LIU, XIANXIANG, YE, HONGZHI
Format:	Artikel
Sprache:	eng
Schlagworte:	Achyranthes - chemistry Achyranthes bidentata polysaccharides Alcohol Animals Antibodies Cell cycle cell proliferation Cell Proliferation - drug effects Chinese medicine chondrocyte Chondrocytes Chondrocytes - cytology Chondrocytes - drug effects Chondrocytes - metabolism Cyclin D1 Cyclin D1 - genetics Cyclin D1 - metabolism Cyclin-dependent kinase 4 Cyclin-Dependent Kinase 4 - genetics Cyclin-Dependent Kinase 4 - metabolism Cyclin-Dependent Kinase 6 - genetics Cyclin-Dependent Kinase 6 - metabolism Cyclin-dependent kinases Deoxyribonucleic acid DNA Flow cytometry G1 Phase - drug effects Kinases Laboratory animals Male Molecular modelling Osteoarthritis Penicillin Phase transitions Polymerase chain reaction Polysaccharides Polysaccharides - chemistry Polysaccharides - pharmacology Proteins Rats Rats, Sprague-Dawley RNA, Messenger - metabolism S phase S Phase - drug effects Traditional Chinese medicine Up-Regulation - drug effects
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!