Clinicopathologic risk factors for recurrence of ovarian endometrioma following laparoscopic cystectomy
Objective To identify epidemiologic risk factors and investigate whether the characteristics of removed ovarian tissue during surgery influence the recurrence of endometriomas. Design Retrospective cohort study. Setting Medical university hospital. Population 248 women with endometriomas. Methods Al...
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| Veröffentlicht in: | Acta obstetricia et gynecologica Scandinavica 2013-03, Vol.92 (3), p.278-284 |
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| container_title | Acta obstetricia et gynecologica Scandinavica |
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| creator | Sengoku, Kazuo Miyamoto, Toshinobu Horikawa, Michiharu Katayama, Hideto Nishiwaki, Kunihiko Kato, Yasuhito Kawanishi, Yasuyuki Saijo, Yasuaki |
| description | Objective
To identify epidemiologic risk factors and investigate whether the characteristics of removed ovarian tissue during surgery influence the recurrence of endometriomas.
Design
Retrospective cohort study.
Setting
Medical university hospital.
Population
248 women with endometriomas.
Methods
All women who had a minimum of 2 years of follow‐up after the laparoscopic excision of endometriomas were analysed retrospectively. Specimens were analysed histologically.
Main outcome measures
Sixteen epidemiologic variables were analysed as possible risk factors for recurrence. The association between the characteristics of removed ovarian tissue (the thickness of the cyst wall, the thickness of ovarian tissue, and the morphological features) and endometrioma recurrence was investigated.
Results
The cumulative incidence of endometriomas reached 42% at 60 months after surgery. We identified only a younger age at surgery as a risk factor, and postoperative pregnancy as a preventive factor. There were no differences in the mean thickness of the cyst wall and the removed ovarian tissue between patients with and without recurrence. No statistically significant associations were found between the morphologic characteristics of removed cyst wall, ovarian tissue, graded on a semi‐quantitative basis, and recurrence.
Conclusions
These results suggest that the rate of endometrioma recurrence had a significant relation to patient age and postoperative pregnancy; however, there was no association between the histological characteristics of the excised tissue and recurrence. |
| doi_str_mv | 10.1111/aogs.12051 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1312661053</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2920066321</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4971-fdbe844ca4cd2e4c63a92fc18f75c887db50cefd043ad623fd28f19725d809cc3</originalsourceid><addsrcrecordid>eNp9kE1PFDEYgBuDkRW5-APMJFyMyWDfttPOHHGjiwYhRgncmm4_1kJnurYz4v57uy5w8EAvTZPnfdL3Qeg14GMo572Kq3wMBDfwDM2AY1xjBmQPzTDGUHPKun30Mueb8iKCtS_QPqHQMQwwQ6t58IPXca3GnzHElddV8vm2ckqPMeXKxVQlq6eU7KBtFV0Vf6vk1VDZwcTejsnHXhUshHjnh1UV1FqlmIuxqPQmj7aI-s0r9NypkO3h_X2ALj99_DE_rc8uFp_nJ2e1Zp2A2pmlbRnTimlDLNOcqo44Da0TjW5bYZYN1tYZzKgynFBnSOugE6QxLe60pgfo7c67TvHXZPMoe5-1DUENNk5ZAgXCOeCGFvToP_QmTmkov9tSgnFOOlGodztKl61ysk6uk-9V2kjAcptfbvPLf_kL_OZeOS17ax7Rh94FgB1w54PdPKGSJxeL7w_SejfjS8w_jzMq3UouqGjk1flC0mv87cOX068S07-nw6EU</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1317466297</pqid></control><display><type>article</type><title>Clinicopathologic risk factors for recurrence of ovarian endometrioma following laparoscopic cystectomy</title><source>MEDLINE</source><source>Wiley Online Library Journals Frontfile Complete</source><creator>Sengoku, Kazuo ; Miyamoto, Toshinobu ; Horikawa, Michiharu ; Katayama, Hideto ; Nishiwaki, Kunihiko ; Kato, Yasuhito ; Kawanishi, Yasuyuki ; Saijo, Yasuaki</creator><creatorcontrib>Sengoku, Kazuo ; Miyamoto, Toshinobu ; Horikawa, Michiharu ; Katayama, Hideto ; Nishiwaki, Kunihiko ; Kato, Yasuhito ; Kawanishi, Yasuyuki ; Saijo, Yasuaki</creatorcontrib><description>Objective
To identify epidemiologic risk factors and investigate whether the characteristics of removed ovarian tissue during surgery influence the recurrence of endometriomas.
Design
Retrospective cohort study.
Setting
Medical university hospital.
Population
248 women with endometriomas.
Methods
All women who had a minimum of 2 years of follow‐up after the laparoscopic excision of endometriomas were analysed retrospectively. Specimens were analysed histologically.
Main outcome measures
Sixteen epidemiologic variables were analysed as possible risk factors for recurrence. The association between the characteristics of removed ovarian tissue (the thickness of the cyst wall, the thickness of ovarian tissue, and the morphological features) and endometrioma recurrence was investigated.
Results
The cumulative incidence of endometriomas reached 42% at 60 months after surgery. We identified only a younger age at surgery as a risk factor, and postoperative pregnancy as a preventive factor. There were no differences in the mean thickness of the cyst wall and the removed ovarian tissue between patients with and without recurrence. No statistically significant associations were found between the morphologic characteristics of removed cyst wall, ovarian tissue, graded on a semi‐quantitative basis, and recurrence.
Conclusions
These results suggest that the rate of endometrioma recurrence had a significant relation to patient age and postoperative pregnancy; however, there was no association between the histological characteristics of the excised tissue and recurrence.</description><identifier>ISSN: 0001-6349</identifier><identifier>EISSN: 1600-0412</identifier><identifier>DOI: 10.1111/aogs.12051</identifier><identifier>PMID: 23194011</identifier><identifier>CODEN: AOGSAE</identifier><language>eng</language><publisher>United States: Blackwell Publishing Ltd</publisher><subject>Adolescent ; Adult ; Age Factors ; Cystectomy ; endometrioma ; Endometriosis - pathology ; Endometriosis - surgery ; Female ; Follow-Up Studies ; Humans ; Laparoscopy ; Middle Aged ; Multivariate Analysis ; Ovarian Diseases - pathology ; Ovarian Diseases - surgery ; ovarian tissue ; Pregnancy ; Proportional Hazards Models ; Recurrence ; Retrospective Studies ; risk factor ; Risk Factors ; Statistics, Nonparametric ; Young Adult</subject><ispartof>Acta obstetricia et gynecologica Scandinavica, 2013-03, Vol.92 (3), p.278-284</ispartof><rights>2012 The Authors Acta Obstetricia et Gynecologica Scandinavica © 2012 Nordic Federation of Societies of Obstetrics and Gynecology</rights><rights>2012 The Authors Acta Obstetricia et Gynecologica Scandinavica © 2012 Nordic Federation of Societies of Obstetrics and Gynecology.</rights><rights>2013 Nordic Federation of Societies of Obstetrics and Gynecology.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4971-fdbe844ca4cd2e4c63a92fc18f75c887db50cefd043ad623fd28f19725d809cc3</citedby><cites>FETCH-LOGICAL-c4971-fdbe844ca4cd2e4c63a92fc18f75c887db50cefd043ad623fd28f19725d809cc3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Faogs.12051$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Faogs.12051$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27901,27902,45550,45551</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23194011$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Sengoku, Kazuo</creatorcontrib><creatorcontrib>Miyamoto, Toshinobu</creatorcontrib><creatorcontrib>Horikawa, Michiharu</creatorcontrib><creatorcontrib>Katayama, Hideto</creatorcontrib><creatorcontrib>Nishiwaki, Kunihiko</creatorcontrib><creatorcontrib>Kato, Yasuhito</creatorcontrib><creatorcontrib>Kawanishi, Yasuyuki</creatorcontrib><creatorcontrib>Saijo, Yasuaki</creatorcontrib><title>Clinicopathologic risk factors for recurrence of ovarian endometrioma following laparoscopic cystectomy</title><title>Acta obstetricia et gynecologica Scandinavica</title><addtitle>Acta Obstet Gynecol Scand</addtitle><description>Objective
To identify epidemiologic risk factors and investigate whether the characteristics of removed ovarian tissue during surgery influence the recurrence of endometriomas.
Design
Retrospective cohort study.
Setting
Medical university hospital.
Population
248 women with endometriomas.
Methods
All women who had a minimum of 2 years of follow‐up after the laparoscopic excision of endometriomas were analysed retrospectively. Specimens were analysed histologically.
Main outcome measures
Sixteen epidemiologic variables were analysed as possible risk factors for recurrence. The association between the characteristics of removed ovarian tissue (the thickness of the cyst wall, the thickness of ovarian tissue, and the morphological features) and endometrioma recurrence was investigated.
Results
The cumulative incidence of endometriomas reached 42% at 60 months after surgery. We identified only a younger age at surgery as a risk factor, and postoperative pregnancy as a preventive factor. There were no differences in the mean thickness of the cyst wall and the removed ovarian tissue between patients with and without recurrence. No statistically significant associations were found between the morphologic characteristics of removed cyst wall, ovarian tissue, graded on a semi‐quantitative basis, and recurrence.
Conclusions
These results suggest that the rate of endometrioma recurrence had a significant relation to patient age and postoperative pregnancy; however, there was no association between the histological characteristics of the excised tissue and recurrence.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Age Factors</subject><subject>Cystectomy</subject><subject>endometrioma</subject><subject>Endometriosis - pathology</subject><subject>Endometriosis - surgery</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Humans</subject><subject>Laparoscopy</subject><subject>Middle Aged</subject><subject>Multivariate Analysis</subject><subject>Ovarian Diseases - pathology</subject><subject>Ovarian Diseases - surgery</subject><subject>ovarian tissue</subject><subject>Pregnancy</subject><subject>Proportional Hazards Models</subject><subject>Recurrence</subject><subject>Retrospective Studies</subject><subject>risk factor</subject><subject>Risk Factors</subject><subject>Statistics, Nonparametric</subject><subject>Young Adult</subject><issn>0001-6349</issn><issn>1600-0412</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kE1PFDEYgBuDkRW5-APMJFyMyWDfttPOHHGjiwYhRgncmm4_1kJnurYz4v57uy5w8EAvTZPnfdL3Qeg14GMo572Kq3wMBDfwDM2AY1xjBmQPzTDGUHPKun30Mueb8iKCtS_QPqHQMQwwQ6t58IPXca3GnzHElddV8vm2ckqPMeXKxVQlq6eU7KBtFV0Vf6vk1VDZwcTejsnHXhUshHjnh1UV1FqlmIuxqPQmj7aI-s0r9NypkO3h_X2ALj99_DE_rc8uFp_nJ2e1Zp2A2pmlbRnTimlDLNOcqo44Da0TjW5bYZYN1tYZzKgynFBnSOugE6QxLe60pgfo7c67TvHXZPMoe5-1DUENNk5ZAgXCOeCGFvToP_QmTmkov9tSgnFOOlGodztKl61ysk6uk-9V2kjAcptfbvPLf_kL_OZeOS17ax7Rh94FgB1w54PdPKGSJxeL7w_SejfjS8w_jzMq3UouqGjk1flC0mv87cOX068S07-nw6EU</recordid><startdate>201303</startdate><enddate>201303</enddate><creator>Sengoku, Kazuo</creator><creator>Miyamoto, Toshinobu</creator><creator>Horikawa, Michiharu</creator><creator>Katayama, Hideto</creator><creator>Nishiwaki, Kunihiko</creator><creator>Kato, Yasuhito</creator><creator>Kawanishi, Yasuyuki</creator><creator>Saijo, Yasuaki</creator><general>Blackwell Publishing Ltd</general><general>John Wiley & Sons, Inc</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>K9.</scope><scope>7X8</scope></search><sort><creationdate>201303</creationdate><title>Clinicopathologic risk factors for recurrence of ovarian endometrioma following laparoscopic cystectomy</title><author>Sengoku, Kazuo ; Miyamoto, Toshinobu ; Horikawa, Michiharu ; Katayama, Hideto ; Nishiwaki, Kunihiko ; Kato, Yasuhito ; Kawanishi, Yasuyuki ; Saijo, Yasuaki</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4971-fdbe844ca4cd2e4c63a92fc18f75c887db50cefd043ad623fd28f19725d809cc3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Age Factors</topic><topic>Cystectomy</topic><topic>endometrioma</topic><topic>Endometriosis - pathology</topic><topic>Endometriosis - surgery</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>Humans</topic><topic>Laparoscopy</topic><topic>Middle Aged</topic><topic>Multivariate Analysis</topic><topic>Ovarian Diseases - pathology</topic><topic>Ovarian Diseases - surgery</topic><topic>ovarian tissue</topic><topic>Pregnancy</topic><topic>Proportional Hazards Models</topic><topic>Recurrence</topic><topic>Retrospective Studies</topic><topic>risk factor</topic><topic>Risk Factors</topic><topic>Statistics, Nonparametric</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Sengoku, Kazuo</creatorcontrib><creatorcontrib>Miyamoto, Toshinobu</creatorcontrib><creatorcontrib>Horikawa, Michiharu</creatorcontrib><creatorcontrib>Katayama, Hideto</creatorcontrib><creatorcontrib>Nishiwaki, Kunihiko</creatorcontrib><creatorcontrib>Kato, Yasuhito</creatorcontrib><creatorcontrib>Kawanishi, Yasuyuki</creatorcontrib><creatorcontrib>Saijo, Yasuaki</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>MEDLINE - Academic</collection><jtitle>Acta obstetricia et gynecologica Scandinavica</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Sengoku, Kazuo</au><au>Miyamoto, Toshinobu</au><au>Horikawa, Michiharu</au><au>Katayama, Hideto</au><au>Nishiwaki, Kunihiko</au><au>Kato, Yasuhito</au><au>Kawanishi, Yasuyuki</au><au>Saijo, Yasuaki</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Clinicopathologic risk factors for recurrence of ovarian endometrioma following laparoscopic cystectomy</atitle><jtitle>Acta obstetricia et gynecologica Scandinavica</jtitle><addtitle>Acta Obstet Gynecol Scand</addtitle><date>2013-03</date><risdate>2013</risdate><volume>92</volume><issue>3</issue><spage>278</spage><epage>284</epage><pages>278-284</pages><issn>0001-6349</issn><eissn>1600-0412</eissn><coden>AOGSAE</coden><abstract>Objective
To identify epidemiologic risk factors and investigate whether the characteristics of removed ovarian tissue during surgery influence the recurrence of endometriomas.
Design
Retrospective cohort study.
Setting
Medical university hospital.
Population
248 women with endometriomas.
Methods
All women who had a minimum of 2 years of follow‐up after the laparoscopic excision of endometriomas were analysed retrospectively. Specimens were analysed histologically.
Main outcome measures
Sixteen epidemiologic variables were analysed as possible risk factors for recurrence. The association between the characteristics of removed ovarian tissue (the thickness of the cyst wall, the thickness of ovarian tissue, and the morphological features) and endometrioma recurrence was investigated.
Results
The cumulative incidence of endometriomas reached 42% at 60 months after surgery. We identified only a younger age at surgery as a risk factor, and postoperative pregnancy as a preventive factor. There were no differences in the mean thickness of the cyst wall and the removed ovarian tissue between patients with and without recurrence. No statistically significant associations were found between the morphologic characteristics of removed cyst wall, ovarian tissue, graded on a semi‐quantitative basis, and recurrence.
Conclusions
These results suggest that the rate of endometrioma recurrence had a significant relation to patient age and postoperative pregnancy; however, there was no association between the histological characteristics of the excised tissue and recurrence.</abstract><cop>United States</cop><pub>Blackwell Publishing Ltd</pub><pmid>23194011</pmid><doi>10.1111/aogs.12051</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record> |
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| ispartof | Acta obstetricia et gynecologica Scandinavica, 2013-03, Vol.92 (3), p.278-284 |
| issn | 0001-6349 1600-0412 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1312661053 |
| source | MEDLINE; Wiley Online Library Journals Frontfile Complete |
| subjects | Adolescent Adult Age Factors Cystectomy endometrioma Endometriosis - pathology Endometriosis - surgery Female Follow-Up Studies Humans Laparoscopy Middle Aged Multivariate Analysis Ovarian Diseases - pathology Ovarian Diseases - surgery ovarian tissue Pregnancy Proportional Hazards Models Recurrence Retrospective Studies risk factor Risk Factors Statistics, Nonparametric Young Adult |
| title | Clinicopathologic risk factors for recurrence of ovarian endometrioma following laparoscopic cystectomy |
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