Esophageal Sphincter Device for Gastroesophageal Reflux Disease

In this trial, a magnetic device to augment the lower esophageal sphincter was implanted in 100 patients with gastroesophageal reflux disease. At 1 year, esophageal acid exposure had decreased and symptoms had improved. Six patients had serious adverse events. The fundamental pathologic abnormality...

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Veröffentlicht in:	The New England journal of medicine 2013-02, Vol.368 (8), p.719-727
Hauptverfasser:	Ganz, Robert A, Peters, Jeffrey H, Horgan, Santiago, Bemelman, Willem A, Dunst, Christy M, Edmundowicz, Steven A, Lipham, John C, Luketich, James D, Melvin, W. Scott, Oelschlager, Brant K, Schlack-Haerer, Steven C, Smith, C. Daniel, Smith, Christopher C, Dunn, Dan, Taiganides, Paul A
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Biological and medical sciences Deglutition Disorders - etiology Dysphagia Esophageal sphincter Esophageal Sphincter, Lower - surgery Esophagitis - etiology Esophagus Female Gastroenterology. Liver. Pancreas. Abdomen Gastroesophageal reflux Gastroesophageal Reflux - complications Gastroesophageal Reflux - drug therapy Gastroesophageal Reflux - surgery General aspects Humans Magnets Male Medical sciences Middle Aged Other diseases. Semiology Patients Prospective Studies Prostheses and Implants - adverse effects Prosthesis Design Proton pump inhibitors Proton Pump Inhibitors - therapeutic use Quality of Life Sphincter Throat Young Adult
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