MYC-induced epigenetic activation of GATA4 in lung adenocarcinoma

Human lung cancer is a disease with high incidence and accounts for most cancer-related deaths in both men and women. Metastasis is a common event in non-small cell lung carcinoma (NSCLC), diminishing the survival chance of the patients with this type of tumor. It has been shown that MYC is involved...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Molecular cancer research 2013-02, Vol.11 (2), p.161-172
Hauptverfasser:	Castro, Inês C, Breiling, Achim, Luetkenhaus, Katharina, Ceteci, Fatih, Hausmann, Simone, Kress, Sebastian, Lyko, Frank, Rudel, Thomas, Rapp, Ulf R
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - genetics Adenocarcinoma - metabolism Adenocarcinoma - pathology Adenocarcinoma of Lung Cell Adhesion - physiology Cell Growth Processes - physiology Cell Line, Tumor DNA Methylation DNA-Binding Proteins - genetics Epigenesis, Genetic Female GATA4 Transcription Factor - biosynthesis GATA4 Transcription Factor - genetics Gene Expression Regulation, Neoplastic Genes, myc Humans Lung Neoplasms - genetics Lung Neoplasms - metabolism Lung Neoplasms - pathology Male Mucin-2 - genetics Promoter Regions, Genetic Proto-Oncogene Proteins - genetics Proto-Oncogene Proteins c-myc - biosynthesis Proto-Oncogene Proteins c-myc - genetics Proto-Oncogene Proteins p21(ras) ras Proteins - genetics Transcription Factors - genetics
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!