Clinical Application of miRNAs a Ways Off: When and If Its Time Comes, Prognostic Tests Will Likely Be First

Clinical Application of miRNAs a Ways Off: When and If Its Time Comes, Prognostic Tests Will Likely Be First

While it remains too early to tell whether microRNAs (miRNAs) will ultimately prove clinically useful, preclinical research findings continue to confirm their central role in controlling cellular pathways. This novel class of nucieotides, about 20-25 nucieotides in length, affects gene expression by...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Genetic engineering & biotechnology news 2012-08, Vol.32 (14), p.52-53
1. Verfasser: Dimond, Patricia F.
Format: Magazinearticle
Sprache:eng
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 53
container_issue 14
container_start_page 52
container_title Genetic engineering & biotechnology news
container_volume 32
creator Dimond, Patricia F.
description While it remains too early to tell whether microRNAs (miRNAs) will ultimately prove clinically useful, preclinical research findings continue to confirm their central role in controlling cellular pathways. This novel class of nucieotides, about 20-25 nucieotides in length, affects gene expression by interacting with messenger RNAs. But unlike siRNAs, miRNAs are encoded in the human genome and function as natural regulators of global gene expression.
doi_str_mv 10.1089/gen.32.14.20
format Magazinearticle
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1291621530</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1291621530</sourcerecordid><originalsourceid>FETCH-LOGICAL-c140t-d1ddee70a0e25852e4f5d6401a7a348cfb92e69959d9cf20a9619c3dbe1d0b283</originalsourceid><addsrcrecordid>eNotkEtLxDAURoMoOI7u_AFdKth6702aNsuh-ILBAVF0FzJ5SKUvm85i_r3VcfWdxeFbHMYuETKEUt1--i7jlKHICI7YAhUv0lJKPP7jPBUFfZyysxi_ACSpQi3YddXUXW1Nk6yGoZlhqvsu6UPS1i_Pq5iY5N3sY7IJ4ZydBNNEf_G_S_Z2f_daPabrzcNTtVqnFgVMqUPnvC_AgKe8zMmLkDspAE1huCht2CryUqlcOWUDgVESleVu69HBlkq-ZFeH32Hsv3c-Trqto_VNYzrf76JGUigJcw6zenNQ7djHOPqgh7FuzbjXCPq3iJ6LaE4ahSbgP7ryUko</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>magazinearticle</recordtype><pqid>1291621530</pqid></control><display><type>magazinearticle</type><title>Clinical Application of miRNAs a Ways Off: When and If Its Time Comes, Prognostic Tests Will Likely Be First</title><source>Alma/SFX Local Collection</source><creator>Dimond, Patricia F.</creator><creatorcontrib>Dimond, Patricia F.</creatorcontrib><description>While it remains too early to tell whether microRNAs (miRNAs) will ultimately prove clinically useful, preclinical research findings continue to confirm their central role in controlling cellular pathways. This novel class of nucieotides, about 20-25 nucieotides in length, affects gene expression by interacting with messenger RNAs. But unlike siRNAs, miRNAs are encoded in the human genome and function as natural regulators of global gene expression.</description><identifier>ISSN: 1935-472X</identifier><identifier>EISSN: 1937-8661</identifier><identifier>DOI: 10.1089/gen.32.14.20</identifier><language>eng</language><ispartof>Genetic engineering &amp; biotechnology news, 2012-08, Vol.32 (14), p.52-53</ispartof><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>780,784,27925</link.rule.ids></links><search><creatorcontrib>Dimond, Patricia F.</creatorcontrib><title>Clinical Application of miRNAs a Ways Off: When and If Its Time Comes, Prognostic Tests Will Likely Be First</title><title>Genetic engineering &amp; biotechnology news</title><description>While it remains too early to tell whether microRNAs (miRNAs) will ultimately prove clinically useful, preclinical research findings continue to confirm their central role in controlling cellular pathways. This novel class of nucieotides, about 20-25 nucieotides in length, affects gene expression by interacting with messenger RNAs. But unlike siRNAs, miRNAs are encoded in the human genome and function as natural regulators of global gene expression.</description><issn>1935-472X</issn><issn>1937-8661</issn><fulltext>true</fulltext><rsrctype>magazinearticle</rsrctype><creationdate>2012</creationdate><recordtype>magazinearticle</recordtype><recordid>eNotkEtLxDAURoMoOI7u_AFdKth6702aNsuh-ILBAVF0FzJ5SKUvm85i_r3VcfWdxeFbHMYuETKEUt1--i7jlKHICI7YAhUv0lJKPP7jPBUFfZyysxi_ACSpQi3YddXUXW1Nk6yGoZlhqvsu6UPS1i_Pq5iY5N3sY7IJ4ZydBNNEf_G_S_Z2f_daPabrzcNTtVqnFgVMqUPnvC_AgKe8zMmLkDspAE1huCht2CryUqlcOWUDgVESleVu69HBlkq-ZFeH32Hsv3c-Trqto_VNYzrf76JGUigJcw6zenNQ7djHOPqgh7FuzbjXCPq3iJ6LaE4ahSbgP7ryUko</recordid><startdate>20120801</startdate><enddate>20120801</enddate><creator>Dimond, Patricia F.</creator><scope>AAYXX</scope><scope>CITATION</scope><scope>7QO</scope><scope>8FD</scope><scope>FR3</scope><scope>P64</scope></search><sort><creationdate>20120801</creationdate><title>Clinical Application of miRNAs a Ways Off</title><author>Dimond, Patricia F.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c140t-d1ddee70a0e25852e4f5d6401a7a348cfb92e69959d9cf20a9619c3dbe1d0b283</frbrgroupid><rsrctype>magazinearticle</rsrctype><prefilter>magazinearticle</prefilter><language>eng</language><creationdate>2012</creationdate><toplevel>online_resources</toplevel><creatorcontrib>Dimond, Patricia F.</creatorcontrib><collection>CrossRef</collection><collection>Biotechnology Research Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><jtitle>Genetic engineering &amp; biotechnology news</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Dimond, Patricia F.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Clinical Application of miRNAs a Ways Off: When and If Its Time Comes, Prognostic Tests Will Likely Be First</atitle><jtitle>Genetic engineering &amp; biotechnology news</jtitle><date>2012-08-01</date><risdate>2012</risdate><volume>32</volume><issue>14</issue><spage>52</spage><epage>53</epage><pages>52-53</pages><issn>1935-472X</issn><eissn>1937-8661</eissn><abstract>While it remains too early to tell whether microRNAs (miRNAs) will ultimately prove clinically useful, preclinical research findings continue to confirm their central role in controlling cellular pathways. This novel class of nucieotides, about 20-25 nucieotides in length, affects gene expression by interacting with messenger RNAs. But unlike siRNAs, miRNAs are encoded in the human genome and function as natural regulators of global gene expression.</abstract><doi>10.1089/gen.32.14.20</doi><tpages>2</tpages></addata></record>
fulltext fulltext
identifier ISSN: 1935-472X
ispartof Genetic engineering & biotechnology news, 2012-08, Vol.32 (14), p.52-53
issn 1935-472X
1937-8661
language eng
recordid cdi_proquest_miscellaneous_1291621530
source Alma/SFX Local Collection
title Clinical Application of miRNAs a Ways Off: When and If Its Time Comes, Prognostic Tests Will Likely Be First
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-27T10%3A27%3A47IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Clinical%20Application%20of%20miRNAs%20a%20Ways%20Off:%20When%20and%20If%20Its%20Time%20Comes,%20Prognostic%20Tests%20Will%20Likely%20Be%20First&rft.jtitle=Genetic%20engineering%20&%20biotechnology%20news&rft.au=Dimond,%20Patricia%20F.&rft.date=2012-08-01&rft.volume=32&rft.issue=14&rft.spage=52&rft.epage=53&rft.pages=52-53&rft.issn=1935-472X&rft.eissn=1937-8661&rft_id=info:doi/10.1089/gen.32.14.20&rft_dat=%3Cproquest_cross%3E1291621530%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1291621530&rft_id=info:pmid/&rfr_iscdi=true