Functional expression of a proton-coupled organic cation (H super(+)/OC) antiporter in human brain capillary endothelial cell line hCMEC/D3, a human blood-brain barrier model

Background: Knowledge of the molecular basis and transport function of the human blood-brain barrier (BBB) is important for not only understanding human cerebral physiology, but also development of new central nervous system (CNS)-acting drugs. However, few studies have been done using human brain c...

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Veröffentlicht in:Fluids and barriers of the CNS 2013-01, Vol.10 (1), p.8-8
Hauptverfasser: Shimomura, Keita, Okura, Takashi, Kato, Sayaka, Couraud, Pierre-Olivier, Schermann, Jean-Michel, Terasaki, Tetsuya, Deguchi, Yoshiharu
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Sprache:eng
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