mRNA In Situ Hybridization (HistoSonda): A New Diagnostic Tool for HER2-Status in Breast Cancer–A Multicentric Spanish Study

Monoclonal therapies could represent baseline-personalized medicine for patients with neoplasia. One of the most successful examples is Trastuzumab, a humanized antibody against epidermal growth factor receptor 2. Human epidermal growth factor receptor 2 (HER2) is a trans-membrane tyrosine kinase co...

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Veröffentlicht in:	Diagnostic molecular pathology 2012-06, Vol.21 (2), p.84-92
Hauptverfasser:	Bernet, Laia, Martinez Benaclocha, Marcos, Castera, Carles, Cano Muñoz, Rafael, Sevilla, Francisco, Alba, Javier, de Dios Barranco, Juan, Cordoba, Alicia, Garcia-Caballero, Tomas, Hardisson, David, de Francisco Hernandez, Javier Martin, Lazaro, Jose Miguel, Polo, Luis, Riu, Francesc, Rezola, Ricardo, Rojo, Federico, Ruiz, Irune, Hernándiz, Ainoha, de la Cámara de las Heras, J.M, Coupe, Victoria M
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies Biomarkers, Tumor - genetics Biomarkers, Tumor - metabolism Breast carcinoma Breast Neoplasms - diagnosis Breast Neoplasms - metabolism Carcinoma, Ductal, Breast - diagnosis Carcinoma, Ductal, Breast - metabolism Data processing Diagnostic Errors Epidermal growth factor receptors ErbB-2 protein Female Humans Immunohistochemistry In Situ Hybridization - methods Molecular Diagnostic Techniques mRNA Neoplasia Prospective Studies Protein-tyrosine kinase Receptor, ErbB-2 - genetics Receptor, ErbB-2 - metabolism Retrospective Studies RNA, Messenger - genetics RNA, Messenger - metabolism Spain Survival trastuzumab
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