Comparative Study on the Inhibitory Effect of Caffeic and Chlorogenic Acids on Key Enzymes Linked to Alzheimer’s Disease and Some Pro-oxidant Induced Oxidative Stress in Rats’ Brain-In Vitro

This study sought to investigate and compare the interaction of caffeic acid and chlorogenic acid on acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), and some pro-oxidants (FeSO 4 , sodium nitroprusside and quinolinic acid) induced oxidative stress in rat brain in vitro. The result reve...

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Veröffentlicht in:	Neurochemical research 2013-02, Vol.38 (2), p.413-419
Hauptverfasser:	Oboh, Ganiyu, Agunloye, Odunayo M., Akinyemi, Ayodele J., Ademiluyi, Adedayo O., Adefegha, Stephen A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylcholine Acetylcholinesterase - metabolism Alzheimer Disease - drug therapy Alzheimer Disease - enzymology Animals Biochemistry Biomedical and Life Sciences Biomedicine Brain - drug effects Brain - enzymology Butyrylcholinesterase - metabolism Caffeic Acids - chemistry Caffeic Acids - pharmacology Caffeic Acids - therapeutic use Cell Biology Chlorogenic Acid - chemistry Chlorogenic Acid - pharmacology Chlorogenic Acid - therapeutic use Cholinesterase Inhibitors - chemistry Cholinesterase Inhibitors - pharmacology Cholinesterase Inhibitors - therapeutic use Male Neurochemistry Neurology Neurosciences Original Paper Oxidative Stress - drug effects Oxidative Stress - physiology Rats Rats, Wistar Reactive Oxygen Species - metabolism
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