The role of dopaminergic transmission through D1-like and D2-like receptors in amphetamine-induced rat ultrasonic vocalizations

Rationale Systemic amphetamine (AMPH) administration increases the rate of 50-kHz ultrasonic vocalizations (USVs) in adult rats and preferentially enhances the ‘trill’ subtype; these effects of AMPH critically depend on noradrenergic transmission, but the possible contributions of dopamine are uncle...

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Veröffentlicht in:	Psychopharmacology 2013-02, Vol.225 (4), p.853-868
Hauptverfasser:	Wright, Jennifer M., Dobosiewicz, May R. S., Clarke, Paul B. S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amphetamine Amphetamine - pharmacology Amphetamines Analysis Animal communication Animals Antagonists Biomedical and Life Sciences Biomedicine Clozapine Dopamine Dopamine - physiology Dopamine Antagonists - pharmacology Dopamine D1 receptors Dopamine D2 Receptor Antagonists Dopamine D2 receptors Dopamine receptors Dose-Response Relationship, Drug Haloperidol Health aspects Locomotor activity Male Neurosciences Neurotransmission Norepinephrine Original Investigation Pharmacology/Toxicology Psychiatry raclopride Rats Rats, Long-Evans Receptors, Dopamine D1 - antagonists & inhibitors Receptors, Dopamine D1 - physiology Receptors, Dopamine D2 - physiology Risperidone Rodents sulpiride Synaptic Transmission - drug effects Synaptic Transmission - physiology Ultrasonics Vocalization behavior Vocalization, Animal - drug effects Vocalization, Animal - physiology
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