Clinical Trial of the Intratumoral Administration of Labeled DC Combined With Systemic Chemotherapy for Esophageal Cancer

Esophageal cancer is a highly aggressive disease, and improved modalities for its treatment are needed. We performed chemoimmunotherapy involving the intratumoral administration of 111In-labeled dendritic cells (DC) in combination with preoperative chemotherapy in 5 esophageal cancer patients. Matur...

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Veröffentlicht in:	Journal of immunotherapy (1997) 2012-07, Vol.35 (6), p.513-521
Hauptverfasser:	FUJIWARA, Shinichi, WADA, Hisashi, SAKAKIBARA, Mitsuru, KANTO, Tatsuya, SHIMOSEGAWA, Eku, HATAZAWA, Jun, TAKAHASHI, Tsuyoshi, KUROKAWA, Yukinori, YAMASAKI, Makoto, NAKAJIMA, Kiyokazu, TAKIGUCHI, Shuji, NAKAYAMA, Eiichi, MIYATA, Hiroshi, MORI, Masaki, DOKI, Yuichiro, KAWADA, Junji, KAWABATA, Ryohei, NISHIKAWA, Hiroyoshi, GNJATIC, Sacha, SEDRAK, Christine, SATO, Eiichi, NAKAMURA, Yurika
Format:	Artikel
Sprache:	eng
Schlagworte:	ADP-ribosyl Cyclase 1 - biosynthesis Antibodies Antigen (tumor-associated) Antigen-presenting cells Antigens, Neoplasm - immunology Antineoplastic agents Biological and medical sciences Cancer Cancer Vaccines - administration & dosage Cancer Vaccines - immunology Cancer Vaccines - therapeutic use Cell culture Cell migration Chemotherapy Clinical trials Dendritic cells Dendritic Cells - immunology Enzyme-linked immunosorbent assay Esophageal Neoplasms - immunology Esophageal Neoplasms - therapy Esophagus Gastroenterology. Liver. Pancreas. Abdomen Hemocyanins Humans Hypersensitivity (delayed) Immunotherapy Immunotherapy, Adoptive Indium Leukocyte migration Lymph nodes Medical sciences Membrane Proteins - immunology NY-ESO-1 protein Pharmacology. Drug treatments Radioimmunotherapy Scintigraphy Skin tests Tumors
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