Evolution of the tissue factor pathway inhibitor-like Kunitz domain-containing protein family in Rhipicephalus microplus

[Display omitted] ► A family of 42 TFPI-like Kunitz proteins was found in Rhipicephalus microplus. ► Ancient and recent gene and domain duplications caused expansion of the family. ► Estimated tick lineage divergence times correspond with those of previous studies. ► Evidence for a whole genome dupl...

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Veröffentlicht in:	International journal for parasitology 2013-01, Vol.43 (1), p.81-94
Hauptverfasser:	Louw, Elizabeth, van der Merwe, Nicolaas A., Neitz, Albert W.H., Maritz-Olivier, Christine
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Arthropod Proteins - genetics Bayesian Markov Chain Monte Carlo Biological and medical sciences Cluster Analysis Computational Biology Duplication Evolution, Molecular Expressed Sequence Tags Fundamental and applied biological sciences. Psychology Ixodidae Kunitz domain Life cycle. Host-agent relationship. Pathogenesis Lipoproteins - genetics Phylogenetic Phylogeny Protozoa Rhipicephalus Rhipicephalus - genetics Rhipicephalus microplus Sequence Homology, Amino Acid Tissue factor pathway inhibitor (TFPI)
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