Immunohistochemical studies of pulmonary large cell neuroendocrine carcinoma: A possible association between staining patterns with neuroendocrine markers and tumor response to chemotherapy

Objective Pulmonary large cell neuroendocrine carcinoma is a rare high-grade malignant tumor. Because large cell neuroendocrine carcinoma is rare, the optimal treatment, including perioperative chemotherapy, has not been defined. We retrospectively analyzed the correlation among the effectiveness of...

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Veröffentlicht in:	The Journal of thoracic and cardiovascular surgery 2013-03, Vol.145 (3), p.839-846
Hauptverfasser:	Tanaka, Yugo, MD, Ogawa, Hiroyuki, MD, Uchino, Kazuya, MD, Ohbayashi, Chiho, MD, Maniwa, Yoshimasa, MD, Nishio, Wataru, MD, Nakao, Atsunori, MD, Yoshimura, Masahiro, MD
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Antineoplastic Agents - therapeutic use Biomarkers, Tumor - analysis Carcinoma, Large Cell - drug therapy Carcinoma, Large Cell - pathology Carcinoma, Large Cell - surgery Carcinoma, Neuroendocrine - drug therapy Carcinoma, Neuroendocrine - pathology Carcinoma, Neuroendocrine - surgery Cardiothoracic Surgery Chromogranin A Combined Modality Therapy Female Humans Immunohistochemistry - methods Lung Neoplasms - drug therapy Lung Neoplasms - pathology Lung Neoplasms - surgery Male Middle Aged Neoplasm Staging Neural Cell Adhesion Molecules Proportional Hazards Models Retrospective Studies Survival Rate Synaptophysin Treatment Outcome
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