Predictive factors for the use of autologous cell saver transfusion in lumbar spinal surgery
Retrospective review. To identify risk factors for cell saver transfusion in lumbar spinal surgery and determine if cell saver transfusions affected intraoperative or postoperative transfusion rates. Cell saver has been used to minimize allogeneic blood transfusion in lumbar spinal surgery. Conflict...
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| Veröffentlicht in: | Spine (Philadelphia, Pa. 1976) Pa. 1976), 2013-02, Vol.38 (4), p.E217-E222 |
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| container_title | Spine (Philadelphia, Pa. 1976) |
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| creator | Owens, 2nd, Roger Kirk Crawford, 3rd, Charles H Djurasovic, Mladen Canan, Chelsea E Burke, Lauren O Bratcher, Kelly R McCarthy, Kathryn J Carreon, Leah Yacat |
| description | Retrospective review.
To identify risk factors for cell saver transfusion in lumbar spinal surgery and determine if cell saver transfusions affected intraoperative or postoperative transfusion rates.
Cell saver has been used to minimize allogeneic blood transfusion in lumbar spinal surgery. Conflicting reports exist, which call into question the efficacy of cell saver use.
We reviewed medical records of randomly selected patients who underwent posterolateral fusion with or without transforaminal interbody fusion from July 2010 to June 2011. Transfusion rates and transfusion-related complications were determined. Binary logistic regression was performed to identify risk factors for use of autologous cell saver transfusion.
There were 178 females and 107 males, with a mean age of 57.2 years. Of the 285 cases, 39 had no cell saver available, 147 had cell saver available but no autologous blood was recovered or transfused and 99 had an autologous cell saver transfusion. Patients who had cell saver transfusion had a higher rate of intraoperative allogeneic blood transfusion (52%) compared with those who did not (22%). There was no significant difference in the rate of postoperative transfusions or transfusion-related reactions between patients who did and did not have cell saver transfusion. Patient's age, smoking status, American Society of Anesthesiologists grade, use of anticoagulants preoperatively, primary or revision surgery, iliac crest bone graft harvest, anesthesiologist, or surgeon had no significant effect on cell saver infusion. Body mass index (odds ratio [OR] = 1.06), number of posterolateral fusion levels fused (OR = 2.50), and number of transforaminal interbody fusions performed (OR = 2.41) were independent risk factors for the use of autologous cell saver transfusion.
Body mass index, multi-level fusion and transforaminal interbody fusion result in increased use of autologous cell saver transfusion in lumbar spinal surgery. Use of autologous cell saver transfusion did not reduce the requirement for intraoperative or postoperative allogeneic blood transfusion.
2. |
| doi_str_mv | 10.1097/BRS.0b013e31827f044e |
| format | Article |
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To identify risk factors for cell saver transfusion in lumbar spinal surgery and determine if cell saver transfusions affected intraoperative or postoperative transfusion rates.
Cell saver has been used to minimize allogeneic blood transfusion in lumbar spinal surgery. Conflicting reports exist, which call into question the efficacy of cell saver use.
We reviewed medical records of randomly selected patients who underwent posterolateral fusion with or without transforaminal interbody fusion from July 2010 to June 2011. Transfusion rates and transfusion-related complications were determined. Binary logistic regression was performed to identify risk factors for use of autologous cell saver transfusion.
There were 178 females and 107 males, with a mean age of 57.2 years. Of the 285 cases, 39 had no cell saver available, 147 had cell saver available but no autologous blood was recovered or transfused and 99 had an autologous cell saver transfusion. Patients who had cell saver transfusion had a higher rate of intraoperative allogeneic blood transfusion (52%) compared with those who did not (22%). There was no significant difference in the rate of postoperative transfusions or transfusion-related reactions between patients who did and did not have cell saver transfusion. Patient's age, smoking status, American Society of Anesthesiologists grade, use of anticoagulants preoperatively, primary or revision surgery, iliac crest bone graft harvest, anesthesiologist, or surgeon had no significant effect on cell saver infusion. Body mass index (odds ratio [OR] = 1.06), number of posterolateral fusion levels fused (OR = 2.50), and number of transforaminal interbody fusions performed (OR = 2.41) were independent risk factors for the use of autologous cell saver transfusion.
Body mass index, multi-level fusion and transforaminal interbody fusion result in increased use of autologous cell saver transfusion in lumbar spinal surgery. Use of autologous cell saver transfusion did not reduce the requirement for intraoperative or postoperative allogeneic blood transfusion.
2.</description><identifier>ISSN: 0362-2436</identifier><identifier>EISSN: 1528-1159</identifier><identifier>DOI: 10.1097/BRS.0b013e31827f044e</identifier><identifier>PMID: 23197016</identifier><language>eng</language><publisher>United States</publisher><subject>Blood Loss, Surgical - prevention & control ; Blood Transfusion, Autologous - adverse effects ; Body Mass Index ; Female ; Humans ; Logistic Models ; Lumbar Vertebrae - surgery ; Male ; Middle Aged ; Odds Ratio ; Operative Blood Salvage - adverse effects ; Operative Blood Salvage - instrumentation ; Postoperative Hemorrhage - etiology ; Postoperative Hemorrhage - therapy ; Retrospective Studies ; Risk Factors ; Spinal Fusion - adverse effects ; Treatment Outcome</subject><ispartof>Spine (Philadelphia, Pa. 1976), 2013-02, Vol.38 (4), p.E217-E222</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c307t-e318a557ec7c1f0abbe5cf8e344d890f526e0585df37df39024dae80ec6f1e863</citedby><cites>FETCH-LOGICAL-c307t-e318a557ec7c1f0abbe5cf8e344d890f526e0585df37df39024dae80ec6f1e863</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27923,27924</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23197016$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Owens, 2nd, Roger Kirk</creatorcontrib><creatorcontrib>Crawford, 3rd, Charles H</creatorcontrib><creatorcontrib>Djurasovic, Mladen</creatorcontrib><creatorcontrib>Canan, Chelsea E</creatorcontrib><creatorcontrib>Burke, Lauren O</creatorcontrib><creatorcontrib>Bratcher, Kelly R</creatorcontrib><creatorcontrib>McCarthy, Kathryn J</creatorcontrib><creatorcontrib>Carreon, Leah Yacat</creatorcontrib><title>Predictive factors for the use of autologous cell saver transfusion in lumbar spinal surgery</title><title>Spine (Philadelphia, Pa. 1976)</title><addtitle>Spine (Phila Pa 1976)</addtitle><description>Retrospective review.
To identify risk factors for cell saver transfusion in lumbar spinal surgery and determine if cell saver transfusions affected intraoperative or postoperative transfusion rates.
Cell saver has been used to minimize allogeneic blood transfusion in lumbar spinal surgery. Conflicting reports exist, which call into question the efficacy of cell saver use.
We reviewed medical records of randomly selected patients who underwent posterolateral fusion with or without transforaminal interbody fusion from July 2010 to June 2011. Transfusion rates and transfusion-related complications were determined. Binary logistic regression was performed to identify risk factors for use of autologous cell saver transfusion.
There were 178 females and 107 males, with a mean age of 57.2 years. Of the 285 cases, 39 had no cell saver available, 147 had cell saver available but no autologous blood was recovered or transfused and 99 had an autologous cell saver transfusion. Patients who had cell saver transfusion had a higher rate of intraoperative allogeneic blood transfusion (52%) compared with those who did not (22%). There was no significant difference in the rate of postoperative transfusions or transfusion-related reactions between patients who did and did not have cell saver transfusion. Patient's age, smoking status, American Society of Anesthesiologists grade, use of anticoagulants preoperatively, primary or revision surgery, iliac crest bone graft harvest, anesthesiologist, or surgeon had no significant effect on cell saver infusion. Body mass index (odds ratio [OR] = 1.06), number of posterolateral fusion levels fused (OR = 2.50), and number of transforaminal interbody fusions performed (OR = 2.41) were independent risk factors for the use of autologous cell saver transfusion.
Body mass index, multi-level fusion and transforaminal interbody fusion result in increased use of autologous cell saver transfusion in lumbar spinal surgery. Use of autologous cell saver transfusion did not reduce the requirement for intraoperative or postoperative allogeneic blood transfusion.
2.</description><subject>Blood Loss, Surgical - prevention & control</subject><subject>Blood Transfusion, Autologous - adverse effects</subject><subject>Body Mass Index</subject><subject>Female</subject><subject>Humans</subject><subject>Logistic Models</subject><subject>Lumbar Vertebrae - surgery</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Odds Ratio</subject><subject>Operative Blood Salvage - adverse effects</subject><subject>Operative Blood Salvage - instrumentation</subject><subject>Postoperative Hemorrhage - etiology</subject><subject>Postoperative Hemorrhage - therapy</subject><subject>Retrospective Studies</subject><subject>Risk Factors</subject><subject>Spinal Fusion - adverse effects</subject><subject>Treatment Outcome</subject><issn>0362-2436</issn><issn>1528-1159</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpdkEtPwzAQhC0EoqXwDxDykUvK2o4T5wgVL6kSiMcNKXKcdQlK42LHlfrvSdXCgcNqLjO7sx8h5wymDIr86ubldQoVMIGCKZ5bSFM8IGMmuUoYk8UhGYPIeMJTkY3ISQhfAJAJVhyTER8kB5aNycezx7oxfbNGarXpnQ_UOk_7T6QxIHWW6ti71i1cDNRg29Kg1zgYvO6CjaFxHW062sZlpT0Nq6bTgyX6BfrNKTmyug14ttcJeb-7fZs9JPOn-8fZ9TwxAvI-2T6gpczR5IZZ0FWF0liFIk1rVYCVPEOQStZW5MMUwNNaowI0mWWoMjEhl7u9K---I4a-XDZh21V3ONQuGVdKQAGSD9Z0ZzXeheDRlivfLLXflAzKLddy4Fr-5zrELvYXYrXE-i_0C1L8ACC4dnI</recordid><startdate>20130215</startdate><enddate>20130215</enddate><creator>Owens, 2nd, Roger Kirk</creator><creator>Crawford, 3rd, Charles H</creator><creator>Djurasovic, Mladen</creator><creator>Canan, Chelsea E</creator><creator>Burke, Lauren O</creator><creator>Bratcher, Kelly R</creator><creator>McCarthy, Kathryn J</creator><creator>Carreon, Leah Yacat</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20130215</creationdate><title>Predictive factors for the use of autologous cell saver transfusion in lumbar spinal surgery</title><author>Owens, 2nd, Roger Kirk ; Crawford, 3rd, Charles H ; Djurasovic, Mladen ; Canan, Chelsea E ; Burke, Lauren O ; Bratcher, Kelly R ; McCarthy, Kathryn J ; Carreon, Leah Yacat</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c307t-e318a557ec7c1f0abbe5cf8e344d890f526e0585df37df39024dae80ec6f1e863</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>Blood Loss, Surgical - prevention & control</topic><topic>Blood Transfusion, Autologous - adverse effects</topic><topic>Body Mass Index</topic><topic>Female</topic><topic>Humans</topic><topic>Logistic Models</topic><topic>Lumbar Vertebrae - surgery</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Odds Ratio</topic><topic>Operative Blood Salvage - adverse effects</topic><topic>Operative Blood Salvage - instrumentation</topic><topic>Postoperative Hemorrhage - etiology</topic><topic>Postoperative Hemorrhage - therapy</topic><topic>Retrospective Studies</topic><topic>Risk Factors</topic><topic>Spinal Fusion - adverse effects</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Owens, 2nd, Roger Kirk</creatorcontrib><creatorcontrib>Crawford, 3rd, Charles H</creatorcontrib><creatorcontrib>Djurasovic, Mladen</creatorcontrib><creatorcontrib>Canan, Chelsea E</creatorcontrib><creatorcontrib>Burke, Lauren O</creatorcontrib><creatorcontrib>Bratcher, Kelly R</creatorcontrib><creatorcontrib>McCarthy, Kathryn J</creatorcontrib><creatorcontrib>Carreon, Leah Yacat</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Spine (Philadelphia, Pa. 1976)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Owens, 2nd, Roger Kirk</au><au>Crawford, 3rd, Charles H</au><au>Djurasovic, Mladen</au><au>Canan, Chelsea E</au><au>Burke, Lauren O</au><au>Bratcher, Kelly R</au><au>McCarthy, Kathryn J</au><au>Carreon, Leah Yacat</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Predictive factors for the use of autologous cell saver transfusion in lumbar spinal surgery</atitle><jtitle>Spine (Philadelphia, Pa. 1976)</jtitle><addtitle>Spine (Phila Pa 1976)</addtitle><date>2013-02-15</date><risdate>2013</risdate><volume>38</volume><issue>4</issue><spage>E217</spage><epage>E222</epage><pages>E217-E222</pages><issn>0362-2436</issn><eissn>1528-1159</eissn><abstract>Retrospective review.
To identify risk factors for cell saver transfusion in lumbar spinal surgery and determine if cell saver transfusions affected intraoperative or postoperative transfusion rates.
Cell saver has been used to minimize allogeneic blood transfusion in lumbar spinal surgery. Conflicting reports exist, which call into question the efficacy of cell saver use.
We reviewed medical records of randomly selected patients who underwent posterolateral fusion with or without transforaminal interbody fusion from July 2010 to June 2011. Transfusion rates and transfusion-related complications were determined. Binary logistic regression was performed to identify risk factors for use of autologous cell saver transfusion.
There were 178 females and 107 males, with a mean age of 57.2 years. Of the 285 cases, 39 had no cell saver available, 147 had cell saver available but no autologous blood was recovered or transfused and 99 had an autologous cell saver transfusion. Patients who had cell saver transfusion had a higher rate of intraoperative allogeneic blood transfusion (52%) compared with those who did not (22%). There was no significant difference in the rate of postoperative transfusions or transfusion-related reactions between patients who did and did not have cell saver transfusion. Patient's age, smoking status, American Society of Anesthesiologists grade, use of anticoagulants preoperatively, primary or revision surgery, iliac crest bone graft harvest, anesthesiologist, or surgeon had no significant effect on cell saver infusion. Body mass index (odds ratio [OR] = 1.06), number of posterolateral fusion levels fused (OR = 2.50), and number of transforaminal interbody fusions performed (OR = 2.41) were independent risk factors for the use of autologous cell saver transfusion.
Body mass index, multi-level fusion and transforaminal interbody fusion result in increased use of autologous cell saver transfusion in lumbar spinal surgery. Use of autologous cell saver transfusion did not reduce the requirement for intraoperative or postoperative allogeneic blood transfusion.
2.</abstract><cop>United States</cop><pmid>23197016</pmid><doi>10.1097/BRS.0b013e31827f044e</doi></addata></record> |
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| identifier | ISSN: 0362-2436 |
| ispartof | Spine (Philadelphia, Pa. 1976), 2013-02, Vol.38 (4), p.E217-E222 |
| issn | 0362-2436 1528-1159 |
| language | eng |
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| source | MEDLINE; Journals@Ovid Complete |
| subjects | Blood Loss, Surgical - prevention & control Blood Transfusion, Autologous - adverse effects Body Mass Index Female Humans Logistic Models Lumbar Vertebrae - surgery Male Middle Aged Odds Ratio Operative Blood Salvage - adverse effects Operative Blood Salvage - instrumentation Postoperative Hemorrhage - etiology Postoperative Hemorrhage - therapy Retrospective Studies Risk Factors Spinal Fusion - adverse effects Treatment Outcome |
| title | Predictive factors for the use of autologous cell saver transfusion in lumbar spinal surgery |
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