Most individuals with treated blood pressures above target receive only one or two antihypertensive drug classes
Background A significant proportion of individuals taking antihypertensive therapies fail to achieve blood pressures
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| Veröffentlicht in: | Internal medicine journal 2013-02, Vol.43 (2), p.137-143 |
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| creator | Campbell, D. J. McGrady, M. Prior, D. L. Coller, J. M. Boffa, U. Shiel, L. Liew, D. Wolfe, R. Stewart, S. Reid, C. M. Krum, H. |
| description | Background
A significant proportion of individuals taking antihypertensive therapies fail to achieve blood pressures |
| doi_str_mv | 10.1111/j.1445-5994.2012.02927.x |
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| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1287887545</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1287887545</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4077-159366794db5fae2da7f8132315949c588773e46e4b01a4569eb4991d33a87553</originalsourceid><addsrcrecordid>eNqNkE9v1DAQxS0EoqXwFZCPXBL8N44PHFAFbdEWJATiaDnxbOslGwfb6e5-e5xu2TM-jN9o3puRfghhSmpa3vtNTYWQldRa1IxQVhOmmar3z9D5afD8UYuKaMLP0KuUNoRQxbV4ic4Y00QzSs_RdBtSxn50_sG72Q4J73y-xzmCzeBwN4Tg8BQhpbkUbLvwADjbeAcZR-jBlzaMw6GUIiLOu4DtmP39YYKYYUyLwcX5DveDTQnSa_RiXc7Am6f_Av38_OnH5XW1-nZ1c_lxVfWCKFVRqXnTKC1cJ9cWmLNq3VLOeBkI3cu2VYqDaEB0hFohGw2d0Jo6zm2rpOQX6N1x7xTDnxlSNlufehgGO0KYk6GsVWWJFIu1PVr7GFKKsDZT9FsbD4YSs_A2G7NgNQtWs_A2j7zNvkTfPl2Zuy24U_Af4GL4cDTs_ACH_15sbm6_LKrkq2Pepwz7U97G36ZRXEnz6-uVabhcfVfi2qz4X-eFnog</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1287887545</pqid></control><display><type>article</type><title>Most individuals with treated blood pressures above target receive only one or two antihypertensive drug classes</title><source>MEDLINE</source><source>Wiley Online Library Journals Frontfile Complete</source><creator>Campbell, D. J. ; McGrady, M. ; Prior, D. L. ; Coller, J. M. ; Boffa, U. ; Shiel, L. ; Liew, D. ; Wolfe, R. ; Stewart, S. ; Reid, C. M. ; Krum, H.</creator><creatorcontrib>Campbell, D. J. ; McGrady, M. ; Prior, D. L. ; Coller, J. M. ; Boffa, U. ; Shiel, L. ; Liew, D. ; Wolfe, R. ; Stewart, S. ; Reid, C. M. ; Krum, H.</creatorcontrib><description>Background
A significant proportion of individuals taking antihypertensive therapies fail to achieve blood pressures <140/90 mmHg. In order to develop strategies for improved treatment of blood pressure, we examined the association of blood pressure control with antihypertensive therapies and clinical and lifestyle factors in a cohort of adults at increased cardiovascular risk.
Methods
A cross‐sectional study of 3994 adults from Melbourne and Shepparton, Australia enrolled in the SCReening Evaluation of the Evolution of New Heart Failure (SCREEN‐HF) study. Inclusion criteria were age ≥60 years with one or more of self‐reported ischaemic or other heart disease, atrial fibrillation, cerebrovascular disease, renal impairment or treatment for hypertension or diabetes for ≥2 years. Exclusion criteria were known heart failure or cardiac abnormality on echocardiography or other imaging. The main outcome measures were the proportion of participants receiving antihypertensive therapy with blood pressures ≥140/90 mmHg and the association of blood pressure control with antihypertensive therapies and clinical and lifestyle factors.
Results
Of 3623 participants (1975 men and 1648 women) receiving antihypertensive therapy, 1867 (52%) had blood pressures ≥140/90 mmHg. Of these 1867 participants, 1483 (79%) were receiving only one or two antihypertensive drug classes. Blood pressures ≥140/90 mmHg were associated with increased age, male sex, waist circumference and log amino‐terminal‐pro‐B‐type natriuretic peptide levels.
Conclusions
Most individuals with treated blood pressures above target receive only one or two antihypertensive drug classes. Prescribing additional antihypertensive drug classes and lifestyle modification may improve blood pressure control in this population of individuals at increased cardiovascular risk.</description><identifier>ISSN: 1444-0903</identifier><identifier>EISSN: 1445-5994</identifier><identifier>DOI: 10.1111/j.1445-5994.2012.02927.x</identifier><identifier>PMID: 22909211</identifier><language>eng</language><publisher>Australia: Blackwell Publishing Ltd</publisher><subject>Aged ; Antihypertensive Agents - classification ; Antihypertensive Agents - therapeutic use ; Blood Pressure - drug effects ; Blood Pressure - physiology ; blood pressure target ; cardiovascular risk ; Cross-Sectional Studies ; Female ; Humans ; hypertension ; Hypertension - drug therapy ; Hypertension - epidemiology ; Hypertension - physiopathology ; Male ; medication ; population cohort ; Risk Reduction Behavior ; Surveys and Questionnaires ; Treatment Outcome</subject><ispartof>Internal medicine journal, 2013-02, Vol.43 (2), p.137-143</ispartof><rights>2012 The Authors; Internal Medicine Journal © 2012 Royal Australasian College of Physicians</rights><rights>2012 The Authors; Internal Medicine Journal © 2012 Royal Australasian College of Physicians.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4077-159366794db5fae2da7f8132315949c588773e46e4b01a4569eb4991d33a87553</citedby><cites>FETCH-LOGICAL-c4077-159366794db5fae2da7f8132315949c588773e46e4b01a4569eb4991d33a87553</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fj.1445-5994.2012.02927.x$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fj.1445-5994.2012.02927.x$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27903,27904,45553,45554</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/22909211$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Campbell, D. J.</creatorcontrib><creatorcontrib>McGrady, M.</creatorcontrib><creatorcontrib>Prior, D. L.</creatorcontrib><creatorcontrib>Coller, J. M.</creatorcontrib><creatorcontrib>Boffa, U.</creatorcontrib><creatorcontrib>Shiel, L.</creatorcontrib><creatorcontrib>Liew, D.</creatorcontrib><creatorcontrib>Wolfe, R.</creatorcontrib><creatorcontrib>Stewart, S.</creatorcontrib><creatorcontrib>Reid, C. M.</creatorcontrib><creatorcontrib>Krum, H.</creatorcontrib><title>Most individuals with treated blood pressures above target receive only one or two antihypertensive drug classes</title><title>Internal medicine journal</title><addtitle>Intern Med J</addtitle><description>Background
A significant proportion of individuals taking antihypertensive therapies fail to achieve blood pressures <140/90 mmHg. In order to develop strategies for improved treatment of blood pressure, we examined the association of blood pressure control with antihypertensive therapies and clinical and lifestyle factors in a cohort of adults at increased cardiovascular risk.
Methods
A cross‐sectional study of 3994 adults from Melbourne and Shepparton, Australia enrolled in the SCReening Evaluation of the Evolution of New Heart Failure (SCREEN‐HF) study. Inclusion criteria were age ≥60 years with one or more of self‐reported ischaemic or other heart disease, atrial fibrillation, cerebrovascular disease, renal impairment or treatment for hypertension or diabetes for ≥2 years. Exclusion criteria were known heart failure or cardiac abnormality on echocardiography or other imaging. The main outcome measures were the proportion of participants receiving antihypertensive therapy with blood pressures ≥140/90 mmHg and the association of blood pressure control with antihypertensive therapies and clinical and lifestyle factors.
Results
Of 3623 participants (1975 men and 1648 women) receiving antihypertensive therapy, 1867 (52%) had blood pressures ≥140/90 mmHg. Of these 1867 participants, 1483 (79%) were receiving only one or two antihypertensive drug classes. Blood pressures ≥140/90 mmHg were associated with increased age, male sex, waist circumference and log amino‐terminal‐pro‐B‐type natriuretic peptide levels.
Conclusions
Most individuals with treated blood pressures above target receive only one or two antihypertensive drug classes. Prescribing additional antihypertensive drug classes and lifestyle modification may improve blood pressure control in this population of individuals at increased cardiovascular risk.</description><subject>Aged</subject><subject>Antihypertensive Agents - classification</subject><subject>Antihypertensive Agents - therapeutic use</subject><subject>Blood Pressure - drug effects</subject><subject>Blood Pressure - physiology</subject><subject>blood pressure target</subject><subject>cardiovascular risk</subject><subject>Cross-Sectional Studies</subject><subject>Female</subject><subject>Humans</subject><subject>hypertension</subject><subject>Hypertension - drug therapy</subject><subject>Hypertension - epidemiology</subject><subject>Hypertension - physiopathology</subject><subject>Male</subject><subject>medication</subject><subject>population cohort</subject><subject>Risk Reduction Behavior</subject><subject>Surveys and Questionnaires</subject><subject>Treatment Outcome</subject><issn>1444-0903</issn><issn>1445-5994</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkE9v1DAQxS0EoqXwFZCPXBL8N44PHFAFbdEWJATiaDnxbOslGwfb6e5-e5xu2TM-jN9o3puRfghhSmpa3vtNTYWQldRa1IxQVhOmmar3z9D5afD8UYuKaMLP0KuUNoRQxbV4ic4Y00QzSs_RdBtSxn50_sG72Q4J73y-xzmCzeBwN4Tg8BQhpbkUbLvwADjbeAcZR-jBlzaMw6GUIiLOu4DtmP39YYKYYUyLwcX5DveDTQnSa_RiXc7Am6f_Av38_OnH5XW1-nZ1c_lxVfWCKFVRqXnTKC1cJ9cWmLNq3VLOeBkI3cu2VYqDaEB0hFohGw2d0Jo6zm2rpOQX6N1x7xTDnxlSNlufehgGO0KYk6GsVWWJFIu1PVr7GFKKsDZT9FsbD4YSs_A2G7NgNQtWs_A2j7zNvkTfPl2Zuy24U_Af4GL4cDTs_ACH_15sbm6_LKrkq2Pepwz7U97G36ZRXEnz6-uVabhcfVfi2qz4X-eFnog</recordid><startdate>201302</startdate><enddate>201302</enddate><creator>Campbell, D. J.</creator><creator>McGrady, M.</creator><creator>Prior, D. L.</creator><creator>Coller, J. M.</creator><creator>Boffa, U.</creator><creator>Shiel, L.</creator><creator>Liew, D.</creator><creator>Wolfe, R.</creator><creator>Stewart, S.</creator><creator>Reid, C. M.</creator><creator>Krum, H.</creator><general>Blackwell Publishing Ltd</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>201302</creationdate><title>Most individuals with treated blood pressures above target receive only one or two antihypertensive drug classes</title><author>Campbell, D. J. ; McGrady, M. ; Prior, D. L. ; Coller, J. M. ; Boffa, U. ; Shiel, L. ; Liew, D. ; Wolfe, R. ; Stewart, S. ; Reid, C. M. ; Krum, H.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4077-159366794db5fae2da7f8132315949c588773e46e4b01a4569eb4991d33a87553</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>Aged</topic><topic>Antihypertensive Agents - classification</topic><topic>Antihypertensive Agents - therapeutic use</topic><topic>Blood Pressure - drug effects</topic><topic>Blood Pressure - physiology</topic><topic>blood pressure target</topic><topic>cardiovascular risk</topic><topic>Cross-Sectional Studies</topic><topic>Female</topic><topic>Humans</topic><topic>hypertension</topic><topic>Hypertension - drug therapy</topic><topic>Hypertension - epidemiology</topic><topic>Hypertension - physiopathology</topic><topic>Male</topic><topic>medication</topic><topic>population cohort</topic><topic>Risk Reduction Behavior</topic><topic>Surveys and Questionnaires</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Campbell, D. J.</creatorcontrib><creatorcontrib>McGrady, M.</creatorcontrib><creatorcontrib>Prior, D. L.</creatorcontrib><creatorcontrib>Coller, J. M.</creatorcontrib><creatorcontrib>Boffa, U.</creatorcontrib><creatorcontrib>Shiel, L.</creatorcontrib><creatorcontrib>Liew, D.</creatorcontrib><creatorcontrib>Wolfe, R.</creatorcontrib><creatorcontrib>Stewart, S.</creatorcontrib><creatorcontrib>Reid, C. M.</creatorcontrib><creatorcontrib>Krum, H.</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Internal medicine journal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Campbell, D. J.</au><au>McGrady, M.</au><au>Prior, D. L.</au><au>Coller, J. M.</au><au>Boffa, U.</au><au>Shiel, L.</au><au>Liew, D.</au><au>Wolfe, R.</au><au>Stewart, S.</au><au>Reid, C. M.</au><au>Krum, H.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Most individuals with treated blood pressures above target receive only one or two antihypertensive drug classes</atitle><jtitle>Internal medicine journal</jtitle><addtitle>Intern Med J</addtitle><date>2013-02</date><risdate>2013</risdate><volume>43</volume><issue>2</issue><spage>137</spage><epage>143</epage><pages>137-143</pages><issn>1444-0903</issn><eissn>1445-5994</eissn><abstract>Background
A significant proportion of individuals taking antihypertensive therapies fail to achieve blood pressures <140/90 mmHg. In order to develop strategies for improved treatment of blood pressure, we examined the association of blood pressure control with antihypertensive therapies and clinical and lifestyle factors in a cohort of adults at increased cardiovascular risk.
Methods
A cross‐sectional study of 3994 adults from Melbourne and Shepparton, Australia enrolled in the SCReening Evaluation of the Evolution of New Heart Failure (SCREEN‐HF) study. Inclusion criteria were age ≥60 years with one or more of self‐reported ischaemic or other heart disease, atrial fibrillation, cerebrovascular disease, renal impairment or treatment for hypertension or diabetes for ≥2 years. Exclusion criteria were known heart failure or cardiac abnormality on echocardiography or other imaging. The main outcome measures were the proportion of participants receiving antihypertensive therapy with blood pressures ≥140/90 mmHg and the association of blood pressure control with antihypertensive therapies and clinical and lifestyle factors.
Results
Of 3623 participants (1975 men and 1648 women) receiving antihypertensive therapy, 1867 (52%) had blood pressures ≥140/90 mmHg. Of these 1867 participants, 1483 (79%) were receiving only one or two antihypertensive drug classes. Blood pressures ≥140/90 mmHg were associated with increased age, male sex, waist circumference and log amino‐terminal‐pro‐B‐type natriuretic peptide levels.
Conclusions
Most individuals with treated blood pressures above target receive only one or two antihypertensive drug classes. Prescribing additional antihypertensive drug classes and lifestyle modification may improve blood pressure control in this population of individuals at increased cardiovascular risk.</abstract><cop>Australia</cop><pub>Blackwell Publishing Ltd</pub><pmid>22909211</pmid><doi>10.1111/j.1445-5994.2012.02927.x</doi><tpages>7</tpages></addata></record> |
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| identifier | ISSN: 1444-0903 |
| ispartof | Internal medicine journal, 2013-02, Vol.43 (2), p.137-143 |
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| source | MEDLINE; Wiley Online Library Journals Frontfile Complete |
| subjects | Aged Antihypertensive Agents - classification Antihypertensive Agents - therapeutic use Blood Pressure - drug effects Blood Pressure - physiology blood pressure target cardiovascular risk Cross-Sectional Studies Female Humans hypertension Hypertension - drug therapy Hypertension - epidemiology Hypertension - physiopathology Male medication population cohort Risk Reduction Behavior Surveys and Questionnaires Treatment Outcome |
| title | Most individuals with treated blood pressures above target receive only one or two antihypertensive drug classes |
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