The incidence and magnitude of fibrinolytic activation in trauma patients

Background: Trauma is a global disease, with over 2.5 million deaths annually from hemorrhage and coagulopathy. Overt hyperfibrinolysis is rare in trauma, and is associated with massive fatal injuries. Paradoxically, clinical trials suggest a much broader indication for antifibrinolytics. Objective...

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Veröffentlicht in:	Journal of thrombosis and haemostasis 2013-02, Vol.11 (2), p.307-314
Hauptverfasser:	RAZA, I., DAVENPORT, R., ROURKE, C., PLATTON, S., MANSON, J., SPOORS, C., KHAN, S., De'ATH, H. D., ALLARD, S., HART, D. P., PASI, K. J., HUNT, B. J., STANWORTH, S., MacCALLUM, P. K., BROHI, K.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult alpha-2-Antiplasmin - metabolism Analysis of Variance Biomarkers - blood Blood Coagulation Disorders - blood Blood Coagulation Disorders - diagnosis Blood Coagulation Disorders - mortality Blood Coagulation Disorders - therapy Blood Transfusion Chi-Square Distribution coagulopathy Female Fibrin Fibrinogen Degradation Products - metabolism Fibrinolysin - metabolism Fibrinolysis Hospitals Humans Incidence Injury Severity Score Male Medical research Middle Aged Mortality Patient Discharge Predictive Value of Tests Prognosis Prospective Studies Respiration, Artificial Risk Factors Thrombelastography thromboelastometry Time Factors Tissue Plasminogen Activator - blood trauma Wounds and Injuries - blood Wounds and Injuries - diagnosis Wounds and Injuries - mortality Wounds and Injuries - therapy
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