Synergistic exposure to noise and styrene and cochlear functionality in a sample of exposed workers: preliminary results

This study is aimed at testing the cochlear functionality using otoacoustic emissions, analyzing the synergistic effects of simultaneous exposure to noise and organic solvents EBTx on workers of a glass-reinforced plastic products factory. Exposure to organic solvents was assessed using ambiental me...

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Veröffentlicht in:Giornale italiano di medicina del lavoro ed ergonomia 2011-07, Vol.33 (3 Suppl), p.130-134
Hauptverfasser: Sisto, R, Cerini, L, Garofani, P, Gatto, M P, Gherardi, M, Gordiani, A, Paci, E, Sanjust, E, Papaleo, B, Tranfo, G
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container_end_page 134
container_issue 3 Suppl
container_start_page 130
container_title Giornale italiano di medicina del lavoro ed ergonomia
container_volume 33
creator Sisto, R
Cerini, L
Garofani, P
Gatto, M P
Gherardi, M
Gordiani, A
Paci, E
Sanjust, E
Papaleo, B
Tranfo, G
description This study is aimed at testing the cochlear functionality using otoacoustic emissions, analyzing the synergistic effects of simultaneous exposure to noise and organic solvents EBTx on workers of a glass-reinforced plastic products factory. Exposure to organic solvents was assessed using ambiental measurements and evaluation of the salivary concentration. Biological monitoring was performed evaluating the urinary concentration of the styrene metabolites. Statistical analysis shows that otoacoustic tests can discriminate between different exposure groups. Significant differences were found between controls and subjects exposed to high styrene and low noise levels, showing the ototoxic effect (at sub-clinical level) of the styrene exposure.
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source MEDLINE; Alma/SFX Local Collection
subjects Adult
Cochlea - drug effects
Cochlea - physiopathology
Female
Humans
Male
Middle Aged
Noise, Occupational - adverse effects
Occupational Exposure - adverse effects
Styrene - adverse effects
title Synergistic exposure to noise and styrene and cochlear functionality in a sample of exposed workers: preliminary results
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