Quality-of-care initiative in patients treated surgically for perforated peptic ulcer

Background: Mortality and morbidity are considerable after treatment for perforated peptic ulcer (PPU). Since 2003, a Danish nationwide quality‐of‐care (QOC) improvement initiative has focused on reducing preoperative delay, and improving perioperative monitoring and care for patients with PPU. The...

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Veröffentlicht in:British journal of surgery 2013-03, Vol.100 (4), p.543-552
Hauptverfasser: Møller, M. H., Larsson, H. J., Rosenstock, S., Jørgensen, H., Johnsen, S. P., Madsen, A. H., Adamsen, S., Jensen, A. G., Zimmermann-Nielsen, E., Thomsen, R. W.
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container_end_page 552
container_issue 4
container_start_page 543
container_title British journal of surgery
container_volume 100
creator Møller, M. H.
Larsson, H. J.
Rosenstock, S.
Jørgensen, H.
Johnsen, S. P.
Madsen, A. H.
Adamsen, S.
Jensen, A. G.
Zimmermann-Nielsen, E.
Thomsen, R. W.
description Background: Mortality and morbidity are considerable after treatment for perforated peptic ulcer (PPU). Since 2003, a Danish nationwide quality‐of‐care (QOC) improvement initiative has focused on reducing preoperative delay, and improving perioperative monitoring and care for patients with PPU. The present study reports the results of this initiative. Methods: This was a nationwide cohort study based on prospectively collected data, involving all hospitals caring for patients with PPU in Denmark. Details of patients treated surgically for PPU between September 2004 and August 2011 were reported to the Danish Clinical Register of Emergency Surgery. Changes in baseline patient characteristics and in seven QOC indicators are presented, including relative risks (RRs) for achievement of the indicators. Results: The study included 2989 patients. An increasing number fulfilled the following four QOC indicators in 2010–2011 compared with the first 2 years of monitoring: preoperative delay no more than 6 h (59·0 versus 54·0 per cent; P = 0·030), daily monitoring of bodyweight (48·0 versus 29·0 per cent; P < 0·001), daily monitoring of fluid balance (79·0 versus 74·0 per cent; P = 0·010) and daily monitoring of vital signs (80·0 versus 68·0 per cent; P < 0·001). A lower proportion of patients had discontinuation of routine prophylactic antibiotics (82·0 versus 90·0 per cent; P < 0·001). Adjusted 30‐day mortality decreased non‐significantly from 2005–2006 to 2010–2011 (adjusted RR 0·87, 95 per cent confidence interval 0·76 to 1·00), whereas the rate of reoperative surgery remained unchanged (adjusted RR 0·98, 0·78 to 1·23). Conclusion: This nationwide quality improvement initiative was associated with reduced preoperative delay and improved perioperative monitoring in patients with PPU. A non‐significant improvement was seen in 30‐day mortality. Copyright © 2012 British Journal of Surgery Society Ltd. Published by John Wiley & Sons, Ltd. No reduction in death or reoperation
doi_str_mv 10.1002/bjs.9028
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H. ; Larsson, H. J. ; Rosenstock, S. ; Jørgensen, H. ; Johnsen, S. P. ; Madsen, A. H. ; Adamsen, S. ; Jensen, A. G. ; Zimmermann-Nielsen, E. ; Thomsen, R. W.</creator><creatorcontrib>Møller, M. H. ; Larsson, H. J. ; Rosenstock, S. ; Jørgensen, H. ; Johnsen, S. P. ; Madsen, A. H. ; Adamsen, S. ; Jensen, A. G. ; Zimmermann-Nielsen, E. ; Thomsen, R. W. ; Danish Clinical Register of Emergency Surgery</creatorcontrib><description>Background: Mortality and morbidity are considerable after treatment for perforated peptic ulcer (PPU). Since 2003, a Danish nationwide quality‐of‐care (QOC) improvement initiative has focused on reducing preoperative delay, and improving perioperative monitoring and care for patients with PPU. The present study reports the results of this initiative. Methods: This was a nationwide cohort study based on prospectively collected data, involving all hospitals caring for patients with PPU in Denmark. Details of patients treated surgically for PPU between September 2004 and August 2011 were reported to the Danish Clinical Register of Emergency Surgery. Changes in baseline patient characteristics and in seven QOC indicators are presented, including relative risks (RRs) for achievement of the indicators. Results: The study included 2989 patients. An increasing number fulfilled the following four QOC indicators in 2010–2011 compared with the first 2 years of monitoring: preoperative delay no more than 6 h (59·0 versus 54·0 per cent; P = 0·030), daily monitoring of bodyweight (48·0 versus 29·0 per cent; P &lt; 0·001), daily monitoring of fluid balance (79·0 versus 74·0 per cent; P = 0·010) and daily monitoring of vital signs (80·0 versus 68·0 per cent; P &lt; 0·001). A lower proportion of patients had discontinuation of routine prophylactic antibiotics (82·0 versus 90·0 per cent; P &lt; 0·001). Adjusted 30‐day mortality decreased non‐significantly from 2005–2006 to 2010–2011 (adjusted RR 0·87, 95 per cent confidence interval 0·76 to 1·00), whereas the rate of reoperative surgery remained unchanged (adjusted RR 0·98, 0·78 to 1·23). Conclusion: This nationwide quality improvement initiative was associated with reduced preoperative delay and improved perioperative monitoring in patients with PPU. A non‐significant improvement was seen in 30‐day mortality. Copyright © 2012 British Journal of Surgery Society Ltd. Published by John Wiley &amp; Sons, Ltd. 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Published by John Wiley &amp; Sons, Ltd.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3548-70da360b7409415a6e72bebf6cfbcf405943921f004a740804794f5c9e8918773</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fbjs.9028$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fbjs.9028$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1416,27915,27916,45565,45566</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23288621$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Møller, M. H.</creatorcontrib><creatorcontrib>Larsson, H. J.</creatorcontrib><creatorcontrib>Rosenstock, S.</creatorcontrib><creatorcontrib>Jørgensen, H.</creatorcontrib><creatorcontrib>Johnsen, S. P.</creatorcontrib><creatorcontrib>Madsen, A. H.</creatorcontrib><creatorcontrib>Adamsen, S.</creatorcontrib><creatorcontrib>Jensen, A. G.</creatorcontrib><creatorcontrib>Zimmermann-Nielsen, E.</creatorcontrib><creatorcontrib>Thomsen, R. W.</creatorcontrib><creatorcontrib>Danish Clinical Register of Emergency Surgery</creatorcontrib><title>Quality-of-care initiative in patients treated surgically for perforated peptic ulcer</title><title>British journal of surgery</title><addtitle>Br J Surg</addtitle><description>Background: Mortality and morbidity are considerable after treatment for perforated peptic ulcer (PPU). Since 2003, a Danish nationwide quality‐of‐care (QOC) improvement initiative has focused on reducing preoperative delay, and improving perioperative monitoring and care for patients with PPU. The present study reports the results of this initiative. Methods: This was a nationwide cohort study based on prospectively collected data, involving all hospitals caring for patients with PPU in Denmark. Details of patients treated surgically for PPU between September 2004 and August 2011 were reported to the Danish Clinical Register of Emergency Surgery. Changes in baseline patient characteristics and in seven QOC indicators are presented, including relative risks (RRs) for achievement of the indicators. Results: The study included 2989 patients. An increasing number fulfilled the following four QOC indicators in 2010–2011 compared with the first 2 years of monitoring: preoperative delay no more than 6 h (59·0 versus 54·0 per cent; P = 0·030), daily monitoring of bodyweight (48·0 versus 29·0 per cent; P &lt; 0·001), daily monitoring of fluid balance (79·0 versus 74·0 per cent; P = 0·010) and daily monitoring of vital signs (80·0 versus 68·0 per cent; P &lt; 0·001). A lower proportion of patients had discontinuation of routine prophylactic antibiotics (82·0 versus 90·0 per cent; P &lt; 0·001). Adjusted 30‐day mortality decreased non‐significantly from 2005–2006 to 2010–2011 (adjusted RR 0·87, 95 per cent confidence interval 0·76 to 1·00), whereas the rate of reoperative surgery remained unchanged (adjusted RR 0·98, 0·78 to 1·23). Conclusion: This nationwide quality improvement initiative was associated with reduced preoperative delay and improved perioperative monitoring in patients with PPU. A non‐significant improvement was seen in 30‐day mortality. Copyright © 2012 British Journal of Surgery Society Ltd. Published by John Wiley &amp; Sons, Ltd. 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J.</creatorcontrib><creatorcontrib>Rosenstock, S.</creatorcontrib><creatorcontrib>Jørgensen, H.</creatorcontrib><creatorcontrib>Johnsen, S. P.</creatorcontrib><creatorcontrib>Madsen, A. H.</creatorcontrib><creatorcontrib>Adamsen, S.</creatorcontrib><creatorcontrib>Jensen, A. G.</creatorcontrib><creatorcontrib>Zimmermann-Nielsen, E.</creatorcontrib><creatorcontrib>Thomsen, R. W.</creatorcontrib><creatorcontrib>Danish Clinical Register of Emergency Surgery</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>MEDLINE - Academic</collection><jtitle>British journal of surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Møller, M. H.</au><au>Larsson, H. J.</au><au>Rosenstock, S.</au><au>Jørgensen, H.</au><au>Johnsen, S. P.</au><au>Madsen, A. H.</au><au>Adamsen, S.</au><au>Jensen, A. G.</au><au>Zimmermann-Nielsen, E.</au><au>Thomsen, R. W.</au><aucorp>Danish Clinical Register of Emergency Surgery</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Quality-of-care initiative in patients treated surgically for perforated peptic ulcer</atitle><jtitle>British journal of surgery</jtitle><addtitle>Br J Surg</addtitle><date>2013-03</date><risdate>2013</risdate><volume>100</volume><issue>4</issue><spage>543</spage><epage>552</epage><pages>543-552</pages><issn>0007-1323</issn><eissn>1365-2168</eissn><coden>BJSUAM</coden><abstract>Background: Mortality and morbidity are considerable after treatment for perforated peptic ulcer (PPU). 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An increasing number fulfilled the following four QOC indicators in 2010–2011 compared with the first 2 years of monitoring: preoperative delay no more than 6 h (59·0 versus 54·0 per cent; P = 0·030), daily monitoring of bodyweight (48·0 versus 29·0 per cent; P &lt; 0·001), daily monitoring of fluid balance (79·0 versus 74·0 per cent; P = 0·010) and daily monitoring of vital signs (80·0 versus 68·0 per cent; P &lt; 0·001). A lower proportion of patients had discontinuation of routine prophylactic antibiotics (82·0 versus 90·0 per cent; P &lt; 0·001). Adjusted 30‐day mortality decreased non‐significantly from 2005–2006 to 2010–2011 (adjusted RR 0·87, 95 per cent confidence interval 0·76 to 1·00), whereas the rate of reoperative surgery remained unchanged (adjusted RR 0·98, 0·78 to 1·23). Conclusion: This nationwide quality improvement initiative was associated with reduced preoperative delay and improved perioperative monitoring in patients with PPU. A non‐significant improvement was seen in 30‐day mortality. Copyright © 2012 British Journal of Surgery Society Ltd. Published by John Wiley &amp; Sons, Ltd. No reduction in death or reoperation</abstract><cop>Chichester, UK</cop><pub>John Wiley &amp; Sons, Ltd</pub><pmid>23288621</pmid><doi>10.1002/bjs.9028</doi><tpages>10</tpages></addata></record>
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subjects Aged
Aged, 80 and over
Denmark
Duodenal Ulcer - surgery
Female
Humans
Male
Middle Aged
Peptic Ulcer Perforation - surgery
Prospective Studies
Quality of Health Care
Recurrence
Reoperation - statistics & numerical data
Stomach Ulcer - surgery
title Quality-of-care initiative in patients treated surgically for perforated peptic ulcer
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