Serotonin syndrome manifesting as patient movement during total intravenous anesthesia with propofol and remifentanil
Abstract A patient who manifested signs of serotonin syndrome during an intravenous anesthetic with remifentanil and propofol is presented. The patient displayed lower extremity clonus, nystagmus, and diaphoresis. At the time of surgery, the patient was being treated with fluoxetine (a selective ser...
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| Veröffentlicht in: | Journal of clinical anesthesia 2013-02, Vol.25 (1), p.52-54 |
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| container_title | Journal of clinical anesthesia |
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| creator | Davis, Jennifer J., MD Buck, Nathan S., MD Swenson, Jeffrey D., MD Johnson, Ken B., MD Greis, Patrick E., MD |
| description | Abstract A patient who manifested signs of serotonin syndrome during an intravenous anesthetic with remifentanil and propofol is presented. The patient displayed lower extremity clonus, nystagmus, and diaphoresis. At the time of surgery, the patient was being treated with fluoxetine (a selective serotonin reuptake inhibitor). A presumptive diagnosis of serotonin syndrome was made intraoperatively and all opioids were discontinued. His symptoms resolved in the Postanesthesia Care Unit without incident. |
| doi_str_mv | 10.1016/j.jclinane.2012.05.002 |
| format | Article |
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The patient displayed lower extremity clonus, nystagmus, and diaphoresis. At the time of surgery, the patient was being treated with fluoxetine (a selective serotonin reuptake inhibitor). A presumptive diagnosis of serotonin syndrome was made intraoperatively and all opioids were discontinued. His symptoms resolved in the Postanesthesia Care Unit without incident.</description><identifier>ISSN: 0952-8180</identifier><identifier>EISSN: 1873-4529</identifier><identifier>DOI: 10.1016/j.jclinane.2012.05.002</identifier><identifier>PMID: 23391344</identifier><language>eng</language><publisher>New York, NY: Elsevier Inc</publisher><subject>Airway management ; Analgesics ; Anesthesia & Perioperative Care ; Anesthesia, Intravenous - methods ; Anesthetics, Intravenous - administration & dosage ; Antidepressants ; Biological and medical sciences ; Catheters ; Drug dosages ; Drug overdose ; Drug toxicity and drugs side effects treatment ; Fluoxetine - adverse effects ; Humans ; Intraoperative Complications - chemically induced ; Intraoperative Complications - diagnosis ; Male ; Medical sciences ; Movement - drug effects ; Myoclonus ; Myoclonus - chemically induced ; Narcotics ; Opioids ; Pain Medicine ; Patients ; Pharmacology. Drug treatments ; Piperidines - administration & dosage ; Propofol - administration & dosage ; Serotonin ; Serotonin syndrome ; Serotonin Syndrome - diagnosis ; Serotonin Syndrome - etiology ; Serotonin Uptake Inhibitors - adverse effects ; Surgery ; Toxicity: nervous system and muscle ; Young Adult</subject><ispartof>Journal of clinical anesthesia, 2013-02, Vol.25 (1), p.52-54</ispartof><rights>Elsevier Inc.</rights><rights>2013 Elsevier Inc.</rights><rights>2014 INIST-CNRS</rights><rights>Copyright © 2013 Elsevier Inc. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c481t-10c8cecde24a24d3180683a1145a81466a3b0f959e1a2474a35a3d64b366dc483</citedby><cites>FETCH-LOGICAL-c481t-10c8cecde24a24d3180683a1145a81466a3b0f959e1a2474a35a3d64b366dc483</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.proquest.com/docview/1287046937?pq-origsite=primo$$EHTML$$P50$$Gproquest$$H</linktohtml><link.rule.ids>314,778,782,3539,27911,27912,45982,64370,64372,64374,72224</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=27130416$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23391344$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Davis, Jennifer J., MD</creatorcontrib><creatorcontrib>Buck, Nathan S., MD</creatorcontrib><creatorcontrib>Swenson, Jeffrey D., MD</creatorcontrib><creatorcontrib>Johnson, Ken B., MD</creatorcontrib><creatorcontrib>Greis, Patrick E., MD</creatorcontrib><title>Serotonin syndrome manifesting as patient movement during total intravenous anesthesia with propofol and remifentanil</title><title>Journal of clinical anesthesia</title><addtitle>J Clin Anesth</addtitle><description>Abstract A patient who manifested signs of serotonin syndrome during an intravenous anesthetic with remifentanil and propofol is presented. The patient displayed lower extremity clonus, nystagmus, and diaphoresis. At the time of surgery, the patient was being treated with fluoxetine (a selective serotonin reuptake inhibitor). A presumptive diagnosis of serotonin syndrome was made intraoperatively and all opioids were discontinued. His symptoms resolved in the Postanesthesia Care Unit without incident.</description><subject>Airway management</subject><subject>Analgesics</subject><subject>Anesthesia & Perioperative Care</subject><subject>Anesthesia, Intravenous - methods</subject><subject>Anesthetics, Intravenous - administration & dosage</subject><subject>Antidepressants</subject><subject>Biological and medical sciences</subject><subject>Catheters</subject><subject>Drug dosages</subject><subject>Drug overdose</subject><subject>Drug toxicity and drugs side effects treatment</subject><subject>Fluoxetine - adverse effects</subject><subject>Humans</subject><subject>Intraoperative Complications - chemically induced</subject><subject>Intraoperative Complications - diagnosis</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Movement - drug effects</subject><subject>Myoclonus</subject><subject>Myoclonus - chemically induced</subject><subject>Narcotics</subject><subject>Opioids</subject><subject>Pain Medicine</subject><subject>Patients</subject><subject>Pharmacology. Drug treatments</subject><subject>Piperidines - administration & dosage</subject><subject>Propofol - administration & dosage</subject><subject>Serotonin</subject><subject>Serotonin syndrome</subject><subject>Serotonin Syndrome - diagnosis</subject><subject>Serotonin Syndrome - etiology</subject><subject>Serotonin Uptake Inhibitors - adverse effects</subject><subject>Surgery</subject><subject>Toxicity: nervous system and muscle</subject><subject>Young Adult</subject><issn>0952-8180</issn><issn>1873-4529</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNqFkk2LFDEQhoMo7jj6F5aACF56zFf3dF_EZfELFjysnkMmqXbTdidjkh6Zf281M-vCXjwlUE-9eaveEHLJ2YYz3rwbNoMdfTABNoJxsWH1hjHxhKx4u5WVqkX3lKxYV4uq5S27IC9yHhhjWODPyYWQsuNSqRWZbyHFEoMPNB-DS3ECOpnge8jFh5_UZLo3xUModIoHmJaLm9NSKrGYkfpQkjlAiHOm6CaXO8je0D--3NF9ivvYxxELjiaYUDUUFB9fkme9GTO8Op9r8uPTx-_XX6qbb5-_Xl_dVFa1vFSc2daCdSCUEcpJnKRppeFc1ablqmmM3LG-qzvgWN8qI2sjXaN2smkcSsg1eXvSRSe_ZzSnJ58tjCM6RcOai7ZGGYk7W5PXj9Ahzimgu4XaMtV0cqGaE2VTzDlBr_fJTyYdNWd6CUYP-j4YvQSjWa0xGGy8PMvPuwncv7b7JBB4cwZMtmbskwnW5wduyyVTvEHuw4kD3NvBQ9LZYjwWnE9gi3bR_9_L-0cSC-Xx1V9whPwwt87Yo2-Xb7T8Ii6wu625_Au0CMWL</recordid><startdate>20130201</startdate><enddate>20130201</enddate><creator>Davis, Jennifer J., MD</creator><creator>Buck, Nathan S., MD</creator><creator>Swenson, Jeffrey D., MD</creator><creator>Johnson, Ken B., MD</creator><creator>Greis, Patrick E., MD</creator><general>Elsevier Inc</general><general>Elsevier</general><general>Elsevier Limited</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>M2O</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>7X8</scope></search><sort><creationdate>20130201</creationdate><title>Serotonin syndrome manifesting as patient movement during total intravenous anesthesia with propofol and remifentanil</title><author>Davis, Jennifer J., MD ; Buck, Nathan S., MD ; Swenson, Jeffrey D., MD ; Johnson, Ken B., MD ; Greis, Patrick E., MD</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c481t-10c8cecde24a24d3180683a1145a81466a3b0f959e1a2474a35a3d64b366dc483</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>Airway management</topic><topic>Analgesics</topic><topic>Anesthesia & Perioperative Care</topic><topic>Anesthesia, Intravenous - methods</topic><topic>Anesthetics, Intravenous - administration & dosage</topic><topic>Antidepressants</topic><topic>Biological and medical sciences</topic><topic>Catheters</topic><topic>Drug dosages</topic><topic>Drug overdose</topic><topic>Drug toxicity and drugs side effects treatment</topic><topic>Fluoxetine - adverse effects</topic><topic>Humans</topic><topic>Intraoperative Complications - chemically induced</topic><topic>Intraoperative Complications - diagnosis</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Movement - drug effects</topic><topic>Myoclonus</topic><topic>Myoclonus - chemically induced</topic><topic>Narcotics</topic><topic>Opioids</topic><topic>Pain Medicine</topic><topic>Patients</topic><topic>Pharmacology. Drug treatments</topic><topic>Piperidines - administration & dosage</topic><topic>Propofol - administration & dosage</topic><topic>Serotonin</topic><topic>Serotonin syndrome</topic><topic>Serotonin Syndrome - diagnosis</topic><topic>Serotonin Syndrome - etiology</topic><topic>Serotonin Uptake Inhibitors - adverse effects</topic><topic>Surgery</topic><topic>Toxicity: nervous system and muscle</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Davis, Jennifer J., MD</creatorcontrib><creatorcontrib>Buck, Nathan S., MD</creatorcontrib><creatorcontrib>Swenson, Jeffrey D., MD</creatorcontrib><creatorcontrib>Johnson, Ken B., MD</creatorcontrib><creatorcontrib>Greis, Patrick E., MD</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Research Library</collection><collection>Research Library (Corporate)</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of clinical anesthesia</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Davis, Jennifer J., MD</au><au>Buck, Nathan S., MD</au><au>Swenson, Jeffrey D., MD</au><au>Johnson, Ken B., MD</au><au>Greis, Patrick E., MD</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Serotonin syndrome manifesting as patient movement during total intravenous anesthesia with propofol and remifentanil</atitle><jtitle>Journal of clinical anesthesia</jtitle><addtitle>J Clin Anesth</addtitle><date>2013-02-01</date><risdate>2013</risdate><volume>25</volume><issue>1</issue><spage>52</spage><epage>54</epage><pages>52-54</pages><issn>0952-8180</issn><eissn>1873-4529</eissn><abstract>Abstract A patient who manifested signs of serotonin syndrome during an intravenous anesthetic with remifentanil and propofol is presented. The patient displayed lower extremity clonus, nystagmus, and diaphoresis. At the time of surgery, the patient was being treated with fluoxetine (a selective serotonin reuptake inhibitor). A presumptive diagnosis of serotonin syndrome was made intraoperatively and all opioids were discontinued. His symptoms resolved in the Postanesthesia Care Unit without incident.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>23391344</pmid><doi>10.1016/j.jclinane.2012.05.002</doi><tpages>3</tpages></addata></record> |
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| ispartof | Journal of clinical anesthesia, 2013-02, Vol.25 (1), p.52-54 |
| issn | 0952-8180 1873-4529 |
| language | eng |
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| source | MEDLINE; ScienceDirect Journals (5 years ago - present); ProQuest Central UK/Ireland |
| subjects | Airway management Analgesics Anesthesia & Perioperative Care Anesthesia, Intravenous - methods Anesthetics, Intravenous - administration & dosage Antidepressants Biological and medical sciences Catheters Drug dosages Drug overdose Drug toxicity and drugs side effects treatment Fluoxetine - adverse effects Humans Intraoperative Complications - chemically induced Intraoperative Complications - diagnosis Male Medical sciences Movement - drug effects Myoclonus Myoclonus - chemically induced Narcotics Opioids Pain Medicine Patients Pharmacology. Drug treatments Piperidines - administration & dosage Propofol - administration & dosage Serotonin Serotonin syndrome Serotonin Syndrome - diagnosis Serotonin Syndrome - etiology Serotonin Uptake Inhibitors - adverse effects Surgery Toxicity: nervous system and muscle Young Adult |
| title | Serotonin syndrome manifesting as patient movement during total intravenous anesthesia with propofol and remifentanil |
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