PTH—A Particularly Tricky Hormone: Why Measure It at All in Kidney Patients?

Plasma parathyroid hormone (PTH) concentrations are commonly measured in the context of CKD, as PTH concentration elevation is typical in this clinical context. Much has been inferred from this raised PTH concentration tendency, both about the state of skeletal integrity and health and also about th...

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Veröffentlicht in:	Clinical journal of the American Society of Nephrology 2013-02, Vol.8 (2), p.299-312
Hauptverfasser:	Garrett, Giorgia, Sardiwal, Sunita, Lamb, Edmund J, Goldsmith, David J A
Format:	Artikel
Sprache:	eng
Schlagworte:	Diagnostic Tests, Routine Hematologic Tests - utilization Humans Parathyroid Hormone - blood Renal Insufficiency, Chronic - blood
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creator	Garrett, Giorgia Sardiwal, Sunita Lamb, Edmund J Goldsmith, David J A
description	Plasma parathyroid hormone (PTH) concentrations are commonly measured in the context of CKD, as PTH concentration elevation is typical in this clinical context. Much has been inferred from this raised PTH concentration tendency, both about the state of skeletal integrity and health and also about the potential clinical outcomes for patients. However, we feel that reliance on PTH concentrations alone is a dangerous substitute for the search for, and use of, more precise and reliable biomarkers. In this article, we rehearse these arguments, bringing together patient-level and analytical considerations for the first time.
doi_str_mv	10.2215/CJN.09580911
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source	MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central; Alma/SFX Local Collection
subjects	Diagnostic Tests, Routine Hematologic Tests - utilization Humans Parathyroid Hormone - blood Renal Insufficiency, Chronic - blood
title	PTH—A Particularly Tricky Hormone: Why Measure It at All in Kidney Patients?
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