Directed Migration of Cortical Interneurons Depends on the Cell-Autonomous Action of Sip1

GABAergic interneurons mainly originate in the medial ganglionic eminence (MGE) of the embryonic ventral telencephalon (VT) and migrate tangentially to the cortex, guided by membrane-bound and secreted factors. We found that Sip1 (Zfhx1b, Zeb2), a transcription factor enriched in migrating cortical...

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Veröffentlicht in:	Neuron (Cambridge, Mass.) Mass.), 2013-01, Vol.77 (1), p.70-82
Hauptverfasser:	van den Berghe, Veronique, Stappers, Elke, Vandesande, Bram, Dimidschstein, Jordane, Kroes, Roel, Francis, Annick, Conidi, Andrea, Lesage, Flore, Dries, Ruben, Cazzola, Silvia, Berx, Geert, Kessaris, Nicoletta, Vanderhaeghen, Pierre, van IJcken, Wilfred, Grosveld, Frank G., Goossens, Steven, Haigh, Jody J., Fishell, Gord, Goffinet, André, Aerts, Stein, Huylebroeck, Danny, Seuntjens, Eve
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Brain slice preparation Cell Movement - physiology Cerebral Cortex - cytology Cerebral Cortex - growth & development Gene Knockout Techniques Interneurons - physiology Mice Mice, Transgenic Migration Neocortex - cytology Neocortex - growth & development Nerve Tissue Proteins - deficiency Nerve Tissue Proteins - genetics Netrin Receptors Neurons Organ Culture Techniques Receptors, Cell Surface - deficiency Receptors, Cell Surface - genetics Rodents Telencephalon - cytology Telencephalon - growth & development Transcription factors
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