Clinical Application for Intra-coronary NanoDDS Devices
Drug eluting stent on the market at present is feared about serious side effects after use (Acute coronary syndrome caused by delayed thrombosis). It is suggested that delayed thrombosis comes from inflammatory reaction, fibrin deposition, and delayed re-endothelialization. We have already succeeded...
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Veröffentlicht in: | Drug Delivery System 2012/09/30, Vol.27(4), pp.275-282 |
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creator | Nakano, Kaku Yufu, Takeo Egashira, Kensuke |
description | Drug eluting stent on the market at present is feared about serious side effects after use (Acute coronary syndrome caused by delayed thrombosis). It is suggested that delayed thrombosis comes from inflammatory reaction, fibrin deposition, and delayed re-endothelialization. We have already succeeded in the development of stent platform that has the function of Nano DDS using electro-deposition coating technology. In this review, we summarize the results of Pulse-Wave Infusion Catheter and statin nanoparticle eluting stent acquiring Proof of Concept by the porcine coronary-arteries models, with describing the outline of stent platform that has the function of Nano DDS. |
doi_str_mv | 10.2745/dds.27.275 |
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It is suggested that delayed thrombosis comes from inflammatory reaction, fibrin deposition, and delayed re-endothelialization. We have already succeeded in the development of stent platform that has the function of Nano DDS using electro-deposition coating technology. 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In this review, we summarize the results of Pulse-Wave Infusion Catheter and statin nanoparticle eluting stent acquiring Proof of Concept by the porcine coronary-arteries models, with describing the outline of stent platform that has the function of Nano DDS.</description><subject>Animal models</subject><subject>Biocompatible Polymer</subject><subject>Delayed in-stent Restenosis</subject><subject>Drug Eluting Stent</subject><subject>Electrodepotion Coating Technology</subject><subject>Nanotechnology</subject><subject>Pleiotropic Effects</subject><subject>Poly (lactic-co-glycolic acid)</subject><subject>Statin</subject><issn>0913-5006</issn><issn>1881-2732</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><recordid>eNo9kE9LAzEQxYMouFYvfoI9irCabJLN7sFDaf1TKHpQz2HMJpqSJmuyFfz2prQWHjOPmR_D8BC6JPimFozf9n3KJosfoYK0LalqQetjVOCO0Ipj3Jyis5RWGLO8JAUSM2e9VeDK6TC4bEYbfGlCLBd-jFCpEIOH-Fs-gw_z-Ws51z9W6XSOTgy4pC_2fYLeH-7fZk_V8uVxMZsuK0U55xURmPO-MaxmGHe8ZiAARMe4anBrakUFBU27hnJQyrSGU2YYazvoDVGYfNAJutrdHWL43ug0yrVNSjsHXodNkqRuOcE414xe71AVQ0pRGzlEu86_S4LlNh2Z08kmawvf7eBVGuFTH1CIo1VO_6Nszx_m6gui1J7-AfgUbD0</recordid><startdate>2012</startdate><enddate>2012</enddate><creator>Nakano, Kaku</creator><creator>Yufu, Takeo</creator><creator>Egashira, Kensuke</creator><general>THE JAPAN SOCIETY OF DRUG DELIVERY SYSTEM</general><scope>AAYXX</scope><scope>CITATION</scope><scope>7QO</scope><scope>8FD</scope><scope>FR3</scope><scope>P64</scope></search><sort><creationdate>2012</creationdate><title>Clinical Application for Intra-coronary NanoDDS Devices</title><author>Nakano, Kaku ; Yufu, Takeo ; Egashira, Kensuke</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3555-17055d6f424009524a7aa7945c608f2c373ae39635accf8f534f4489adf1c01b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng ; jpn</language><creationdate>2012</creationdate><topic>Animal models</topic><topic>Biocompatible Polymer</topic><topic>Delayed in-stent Restenosis</topic><topic>Drug Eluting Stent</topic><topic>Electrodepotion Coating Technology</topic><topic>Nanotechnology</topic><topic>Pleiotropic Effects</topic><topic>Poly (lactic-co-glycolic acid)</topic><topic>Statin</topic><toplevel>online_resources</toplevel><creatorcontrib>Nakano, Kaku</creatorcontrib><creatorcontrib>Yufu, Takeo</creatorcontrib><creatorcontrib>Egashira, Kensuke</creatorcontrib><collection>CrossRef</collection><collection>Biotechnology Research Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><jtitle>Drug Delivery System</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Nakano, Kaku</au><au>Yufu, Takeo</au><au>Egashira, Kensuke</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Clinical Application for Intra-coronary NanoDDS Devices</atitle><jtitle>Drug Delivery System</jtitle><addtitle>DDS</addtitle><date>2012</date><risdate>2012</risdate><volume>27</volume><issue>4</issue><spage>275</spage><epage>282</epage><pages>275-282</pages><issn>0913-5006</issn><eissn>1881-2732</eissn><abstract>Drug eluting stent on the market at present is feared about serious side effects after use (Acute coronary syndrome caused by delayed thrombosis). 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source | J-STAGE Free; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
subjects | Animal models Biocompatible Polymer Delayed in-stent Restenosis Drug Eluting Stent Electrodepotion Coating Technology Nanotechnology Pleiotropic Effects Poly (lactic-co-glycolic acid) Statin |
title | Clinical Application for Intra-coronary NanoDDS Devices |
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