Internist Diagnosis and Management of Chronic Hepatitis B Virus Infection
Abstract Chronic infection with the hepatitis B virus can lead to hepatocellular carcinoma and cirrhosis in up to 25% of infected individuals. As many as 2 million individuals in the US may have chronic hepatitis B infection, most of whom immigrated to the US from hepatitis B-endemic regions of the...
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| Veröffentlicht in: | The American journal of medicine 2012-11, Vol.125 (11), p.1063-1067 |
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| container_title | The American journal of medicine |
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| creator | McMahon, Brian J., MD Block, Joan, RN, BSN Haber, Barbara, MD London, Thomas, MD McHugh, James A., MD Perrillo, Robert, MD Neubauer, Richard, MD |
| description | Abstract Chronic infection with the hepatitis B virus can lead to hepatocellular carcinoma and cirrhosis in up to 25% of infected individuals. As many as 2 million individuals in the US may have chronic hepatitis B infection, most of whom immigrated to the US from hepatitis B-endemic regions of the world. A 2010 report from the Institute of Medicine noted that two thirds of patients with hepatitis B are unaware of their infection, and most health care providers do not screen for hepatitis B or know how to manage hepatitis B-positive patients. In 2010, the Hepatitis B Foundation convened a group of primary care providers to consider the existing evidenced-based recommendations and strategies for implementation of hepatitis B screening into routine practice. The group designed an easy-to-use algorithm for screening, initial evaluation, ongoing management, and referral to a subspecialist when appropriate. Internal medicine specialists, including primary care providers and subspecialists, need to understand the steps they can take to address this often under-recognized disorder. |
| doi_str_mv | 10.1016/j.amjmed.2012.03.010 |
| format | Article |
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As many as 2 million individuals in the US may have chronic hepatitis B infection, most of whom immigrated to the US from hepatitis B-endemic regions of the world. A 2010 report from the Institute of Medicine noted that two thirds of patients with hepatitis B are unaware of their infection, and most health care providers do not screen for hepatitis B or know how to manage hepatitis B-positive patients. In 2010, the Hepatitis B Foundation convened a group of primary care providers to consider the existing evidenced-based recommendations and strategies for implementation of hepatitis B screening into routine practice. The group designed an easy-to-use algorithm for screening, initial evaluation, ongoing management, and referral to a subspecialist when appropriate. Internal medicine specialists, including primary care providers and subspecialists, need to understand the steps they can take to address this often under-recognized disorder.</description><identifier>ISSN: 0002-9343</identifier><identifier>EISSN: 1555-7162</identifier><identifier>DOI: 10.1016/j.amjmed.2012.03.010</identifier><identifier>PMID: 23098862</identifier><identifier>CODEN: AJMEAZ</identifier><language>eng</language><publisher>New York, NY: Elsevier Inc</publisher><subject>Algorithms ; Biological and medical sciences ; Carcinoma, Hepatocellular - prevention & control ; Chronic ; Disease Management ; Female ; General aspects ; Health participants ; Hepatitis ; Hepatitis B ; Hepatitis B Vaccines - administration & dosage ; Hepatitis B virus ; Hepatitis B, Chronic - diagnosis ; Hepatitis B, Chronic - prevention & control ; Hepatitis B, Chronic - therapy ; Human viral diseases ; Humans ; Infectious diseases ; Internal Medicine ; Liver ; Liver Neoplasms - prevention & control ; Male ; Medical diagnosis ; Medical sciences ; Medical screening ; Public health. Hygiene ; Public health. Hygiene-occupational medicine ; Screening ; Viral diseases ; Viral hepatitis</subject><ispartof>The American journal of medicine, 2012-11, Vol.125 (11), p.1063-1067</ispartof><rights>Elsevier Inc.</rights><rights>2012 Elsevier Inc.</rights><rights>2015 INIST-CNRS</rights><rights>Copyright © 2012 Elsevier Inc. All rights reserved.</rights><rights>Copyright Elsevier Science Ltd. Nov 2012</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c508t-1887ddac1854d6610b8780ef16ee02c5142f1ef769a19e9e20a0345edb9b60ac3</citedby><cites>FETCH-LOGICAL-c508t-1887ddac1854d6610b8780ef16ee02c5142f1ef769a19e9e20a0345edb9b60ac3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0002934312003324$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=26569405$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23098862$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>McMahon, Brian J., MD</creatorcontrib><creatorcontrib>Block, Joan, RN, BSN</creatorcontrib><creatorcontrib>Haber, Barbara, MD</creatorcontrib><creatorcontrib>London, Thomas, MD</creatorcontrib><creatorcontrib>McHugh, James A., MD</creatorcontrib><creatorcontrib>Perrillo, Robert, MD</creatorcontrib><creatorcontrib>Neubauer, Richard, MD</creatorcontrib><title>Internist Diagnosis and Management of Chronic Hepatitis B Virus Infection</title><title>The American journal of medicine</title><addtitle>Am J Med</addtitle><description>Abstract Chronic infection with the hepatitis B virus can lead to hepatocellular carcinoma and cirrhosis in up to 25% of infected individuals. As many as 2 million individuals in the US may have chronic hepatitis B infection, most of whom immigrated to the US from hepatitis B-endemic regions of the world. A 2010 report from the Institute of Medicine noted that two thirds of patients with hepatitis B are unaware of their infection, and most health care providers do not screen for hepatitis B or know how to manage hepatitis B-positive patients. In 2010, the Hepatitis B Foundation convened a group of primary care providers to consider the existing evidenced-based recommendations and strategies for implementation of hepatitis B screening into routine practice. The group designed an easy-to-use algorithm for screening, initial evaluation, ongoing management, and referral to a subspecialist when appropriate. Internal medicine specialists, including primary care providers and subspecialists, need to understand the steps they can take to address this often under-recognized disorder.</description><subject>Algorithms</subject><subject>Biological and medical sciences</subject><subject>Carcinoma, Hepatocellular - prevention & control</subject><subject>Chronic</subject><subject>Disease Management</subject><subject>Female</subject><subject>General aspects</subject><subject>Health participants</subject><subject>Hepatitis</subject><subject>Hepatitis B</subject><subject>Hepatitis B Vaccines - administration & dosage</subject><subject>Hepatitis B virus</subject><subject>Hepatitis B, Chronic - diagnosis</subject><subject>Hepatitis B, Chronic - prevention & control</subject><subject>Hepatitis B, Chronic - therapy</subject><subject>Human viral diseases</subject><subject>Humans</subject><subject>Infectious diseases</subject><subject>Internal Medicine</subject><subject>Liver</subject><subject>Liver Neoplasms - prevention & control</subject><subject>Male</subject><subject>Medical diagnosis</subject><subject>Medical sciences</subject><subject>Medical screening</subject><subject>Public health. Hygiene</subject><subject>Public health. Hygiene-occupational medicine</subject><subject>Screening</subject><subject>Viral diseases</subject><subject>Viral hepatitis</subject><issn>0002-9343</issn><issn>1555-7162</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkl2L1DAUhoMo7rj6D0QKInjTepI0aXIj6PixAyte-HEbMunpmtqms0kr7L83ZWZZ2Ju9CiHPeck5zyHkJYWKApXv-sqO_YhtxYCyCngFFB6RDRVClA2V7DHZAAArNa_5GXmWUp-voIV8Ss4YB62UZBuy24UZY_BpLj55exWm5FNhQ1t8s8Fe4YhhLqau2P6JU_CuuMCDnf2cmY_Fbx-XVOxCh272U3hOnnR2SPjidJ6TX18-_9xelJffv-62Hy5LJ0DNJVWqaVvrqBJ1KyWFvWoUYEclIjAnaM06il0jtaUaNTKwwGuB7V7vJVjHz8nbY-4hTtcLptmMPjkcBhtwWpKhTAnQjGv1MErztFjDtc7o63toPy0x5EYypRuhuYY1sD5SLk4pRezMIfrRxhtDwaxWTG-OVsxqxQA32Uoue3UKX_br223RrYYMvDkBNjk7dNEG59MdJ4XUNYjMvT9ymAf8z2M0yXkMDlsfswXTTv6hn9wPcIPPYu3wF28w3fVsUq4xP9YNWheIMgDOWc3_A3q_vp0</recordid><startdate>20121101</startdate><enddate>20121101</enddate><creator>McMahon, Brian J., MD</creator><creator>Block, Joan, RN, BSN</creator><creator>Haber, Barbara, MD</creator><creator>London, Thomas, MD</creator><creator>McHugh, James A., MD</creator><creator>Perrillo, Robert, MD</creator><creator>Neubauer, Richard, MD</creator><general>Elsevier Inc</general><general>Elsevier</general><general>Elsevier Sequoia S.A</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T5</scope><scope>7TK</scope><scope>7TO</scope><scope>7TS</scope><scope>7U9</scope><scope>H94</scope><scope>K9.</scope><scope>7X8</scope></search><sort><creationdate>20121101</creationdate><title>Internist Diagnosis and Management of Chronic Hepatitis B Virus Infection</title><author>McMahon, Brian J., MD ; Block, Joan, RN, BSN ; Haber, Barbara, MD ; London, Thomas, MD ; McHugh, James A., MD ; Perrillo, Robert, MD ; Neubauer, Richard, MD</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c508t-1887ddac1854d6610b8780ef16ee02c5142f1ef769a19e9e20a0345edb9b60ac3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Algorithms</topic><topic>Biological and medical sciences</topic><topic>Carcinoma, Hepatocellular - prevention & control</topic><topic>Chronic</topic><topic>Disease Management</topic><topic>Female</topic><topic>General aspects</topic><topic>Health participants</topic><topic>Hepatitis</topic><topic>Hepatitis B</topic><topic>Hepatitis B Vaccines - administration & dosage</topic><topic>Hepatitis B virus</topic><topic>Hepatitis B, Chronic - diagnosis</topic><topic>Hepatitis B, Chronic - prevention & control</topic><topic>Hepatitis B, Chronic - therapy</topic><topic>Human viral diseases</topic><topic>Humans</topic><topic>Infectious diseases</topic><topic>Internal Medicine</topic><topic>Liver</topic><topic>Liver Neoplasms - prevention & control</topic><topic>Male</topic><topic>Medical diagnosis</topic><topic>Medical sciences</topic><topic>Medical screening</topic><topic>Public health. Hygiene</topic><topic>Public health. Hygiene-occupational medicine</topic><topic>Screening</topic><topic>Viral diseases</topic><topic>Viral hepatitis</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>McMahon, Brian J., MD</creatorcontrib><creatorcontrib>Block, Joan, RN, BSN</creatorcontrib><creatorcontrib>Haber, Barbara, MD</creatorcontrib><creatorcontrib>London, Thomas, MD</creatorcontrib><creatorcontrib>McHugh, James A., MD</creatorcontrib><creatorcontrib>Perrillo, Robert, MD</creatorcontrib><creatorcontrib>Neubauer, Richard, MD</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Immunology Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>Oncogenes and Growth Factors Abstracts</collection><collection>Physical Education Index</collection><collection>Virology and AIDS Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>MEDLINE - Academic</collection><jtitle>The American journal of medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>McMahon, Brian J., MD</au><au>Block, Joan, RN, BSN</au><au>Haber, Barbara, MD</au><au>London, Thomas, MD</au><au>McHugh, James A., MD</au><au>Perrillo, Robert, MD</au><au>Neubauer, Richard, MD</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Internist Diagnosis and Management of Chronic Hepatitis B Virus Infection</atitle><jtitle>The American journal of medicine</jtitle><addtitle>Am J Med</addtitle><date>2012-11-01</date><risdate>2012</risdate><volume>125</volume><issue>11</issue><spage>1063</spage><epage>1067</epage><pages>1063-1067</pages><issn>0002-9343</issn><eissn>1555-7162</eissn><coden>AJMEAZ</coden><abstract>Abstract Chronic infection with the hepatitis B virus can lead to hepatocellular carcinoma and cirrhosis in up to 25% of infected individuals. As many as 2 million individuals in the US may have chronic hepatitis B infection, most of whom immigrated to the US from hepatitis B-endemic regions of the world. A 2010 report from the Institute of Medicine noted that two thirds of patients with hepatitis B are unaware of their infection, and most health care providers do not screen for hepatitis B or know how to manage hepatitis B-positive patients. In 2010, the Hepatitis B Foundation convened a group of primary care providers to consider the existing evidenced-based recommendations and strategies for implementation of hepatitis B screening into routine practice. The group designed an easy-to-use algorithm for screening, initial evaluation, ongoing management, and referral to a subspecialist when appropriate. Internal medicine specialists, including primary care providers and subspecialists, need to understand the steps they can take to address this often under-recognized disorder.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>23098862</pmid><doi>10.1016/j.amjmed.2012.03.010</doi><tpages>5</tpages></addata></record> |
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| subjects | Algorithms Biological and medical sciences Carcinoma, Hepatocellular - prevention & control Chronic Disease Management Female General aspects Health participants Hepatitis Hepatitis B Hepatitis B Vaccines - administration & dosage Hepatitis B virus Hepatitis B, Chronic - diagnosis Hepatitis B, Chronic - prevention & control Hepatitis B, Chronic - therapy Human viral diseases Humans Infectious diseases Internal Medicine Liver Liver Neoplasms - prevention & control Male Medical diagnosis Medical sciences Medical screening Public health. Hygiene Public health. Hygiene-occupational medicine Screening Viral diseases Viral hepatitis |
| title | Internist Diagnosis and Management of Chronic Hepatitis B Virus Infection |
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