Neuroprotective changes of thalamic degeneration-related gene expression by acupuncture in an MPTP mouse model of parkinsonism: Microarray analysis

Acupuncture stimulations at GB34 and LR3 inhibit the reduction of tyrosine hydroxylase in the nigrostriatal dopaminergic neurons in the parkinsonism animal models. Especially, behavioral tests showed that acupuncture stimulations improved the motor dysfunction in a previous study by almost 87.7%. Th...

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Veröffentlicht in:	Gene 2013-02, Vol.515 (2), p.329-338
Hauptverfasser:	Yeo, Sujung, Choi, Yeong-Gon, Hong, Yeon-Mi, Lim, Sabina
Format:	Artikel
Sprache:	eng
Schlagworte:	Acupoints acupuncture Acupuncture Therapy animal models Animals Differentially expressed genes Disease Models, Animal Dopaminergic Neurons - enzymology Gene array Gene Expression gene expression regulation Gene Expression Regulation, Enzymologic genes Male Mice Mice, Inbred C57BL microarray technology MPTP Poisoning - enzymology MPTP Poisoning - pathology MPTP Poisoning - therapy Neurodegeneration neurons Oligonucleotide Array Sequence Analysis Parkinson disease Parkinson's disease poisoning reverse transcriptase polymerase chain reaction Signal Transduction - genetics Substantia Nigra - enzymology Substantia Nigra - pathology thalamus Thalamus - enzymology Thalamus - pathology Transcriptome Tyrosine 3-Monooxygenase - genetics Tyrosine 3-Monooxygenase - metabolism
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