Experimental model for reproduction of canine visceral leishmaniosis by Leishmania infantum

In this report an experimental model of Leishmania infantum (L. infantum) infection in dogs is described. The data presented are derived from an overall and comparative analysis of the clinical outcomes of three groups of dogs intravenously infected with 500,000 promastigotes on different dates (200...

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Veröffentlicht in:	Veterinary parasitology 2013-02, Vol.192 (1-3), p.118-128
Hauptverfasser:	Fernández-Cotrina, J., Iniesta, V., Belinchón-Lorenzo, S., Muñoz-Madrid, R., Serrano, F., Parejo, J.C., Gómez-Gordo, L., Soto, M., Alonso, C., Gómez-Nieto, L.C.
Format:	Artikel
Sprache:	eng
Schlagworte:	amastigotes Animal model Animals Antibodies, Protozoan - biosynthesis Antibodies, Protozoan - blood Antigens, Protozoan - immunology Cricetinae Disease reproduction disease resistance Dog Dog Diseases - immunology Dog Diseases - parasitology Dogs Enzyme-Linked Immunosorbent Assay - veterinary Experimental infection Female hamsters histopathology immune response intravenous injection Kidney - parasitology Kidney - pathology Leishmania infantum Leishmania infantum - growth & development Leishmania infantum - immunology Leishmaniasis, Visceral - immunology Leishmaniasis, Visceral - parasitology Leishmaniasis, Visceral - veterinary Liver - parasitology Liver - pathology Lymph Nodes - parasitology Male necropsy parasite load parasites promastigotes Real-Time Polymerase Chain Reaction - veterinary reproduction spleen Spleen - parasitology Spleen - pathology vaccines visceral leishmaniasis
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