Similar predictions of etravirine sensitivity regardless of genotypic testing method used: comparison of available scoring systems

The aims of this study were to compare various genotypic scoring systems commonly used to predict virological outcome to etravirine, and examine their concordance with etravirine phenotypic susceptibility. Six etravirine genotypic scoring systems were assessed: Tibotec 2010 (based on 20 mutations; T...

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Veröffentlicht in:	Antiviral therapy 2012-01, Vol.17 (8), p.1571-1579
Hauptverfasser:	VINGERHOETS, Johan, NIJS, Steven, TAMBUYZER, Lotke, HOOGSTOEL, Annemie, ANDERSON, David, PICCHIO, Gaston
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-HIV Agents - pharmacology Anti-HIV Agents - therapeutic use Antibiotics. Antiinfectious agents. Antiparasitic agents Antiviral agents Biological and medical sciences Clinical trials Data processing Drug Resistance, Viral - genetics Genetic Association Studies Genotype Genotypes Genotyping Techniques HIV Infections - diagnosis HIV Infections - drug therapy HIV Infections - virology HIV-1 - drug effects HIV-1 - genetics Human immunodeficiency virus 1 Humans Medical sciences Mutation Pharmacology. Drug treatments Phenotype Prognosis Pyridazines - pharmacology Pyridazines - therapeutic use RNA Treatment Outcome
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