Histone lysine methyltransferase, suppressor of variegation 3‐9 homolog 1, promotes hepatocellular carcinoma progression and is negatively regulated by microRNA‐125b

Hepatocellular carcinoma (HCC) is a major liver malignancy. We previously demonstrated that deregulation of epigenetic regulators is a common event in human HCC. Suppressor of variegation 3‐9 homolog 1 (SUV39H1), the prototype of histone methyltransferase, is the major enzyme responsible for histone...

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Veröffentlicht in:Hepatology (Baltimore, Md.) Md.), 2013-02, Vol.57 (2), p.637-647
Hauptverfasser: Ngo‐Yin Fan, Dorothy, Ho‐Ching Tsang, Felice, Hoi‐Kam Tam, Aegean, Leung‐Kuen Au, Sandy, Chak‐Lui Wong, Carmen, Wei, Lai, Man‐Fong Lee, Joyce, He, Xianghuo, Oi‐Lin Ng, Irene, Wong, Chun‐Ming
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Sprache:eng
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