The clinical significance of a new classification algorithm in Chinese DLBCL cases
To investigate the clinicopathologic features, pathogenesis, diagnostic criteria and the relationship between different classification models and prognosis in Chinese patients with DLBCL, and try to look for the most appropriate classification model to predict clinical prognosis and therapeutic resp...
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| Veröffentlicht in: | Zhōnghuá xuèyèxué zázhì 2012-10, Vol.33 (10), p.801-804 |
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| container_title | Zhōnghuá xuèyèxué zázhì |
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| creator | Li, Min Liu, Cui-ling Yin, Wen-juan He, Yao-xin Xue, Xue-min Duan, Ze-jun Gao, Zi-fen |
| description | To investigate the clinicopathologic features, pathogenesis, diagnostic criteria and the relationship between different classification models and prognosis in Chinese patients with DLBCL, and try to look for the most appropriate classification model to predict clinical prognosis and therapeutic responses for Chinese patients with DLBCL.
181 cases of Chinese DLBCLs diagnosed according to the WHO 2008 classification were collected. Standard two-step Envision method of immunohistochemical staining was used to assess the expressions of CD20, CD3ε, CD79a, CD10, Mum-1, Bcl-6, GCET-1, FOXP1 and Ki-67. The phenotypic classifications were assessed according to the standard of Hans model and Chan model. Data were analyzed by χ(2) test and Life Table survival analysis with the SPSS14.0 statistical package.
The ratio of male to female in this cohort was 1.26:1. The median age of all patients was 57 yrs with the average age of 53.5 yrs. Of 61 cases (33.7%) primarily showed lymph node involvement. Gastrointestinal tract as |
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181 cases of Chinese DLBCLs diagnosed according to the WHO 2008 classification were collected. Standard two-step Envision method of immunohistochemical staining was used to assess the expressions of CD20, CD3ε, CD79a, CD10, Mum-1, Bcl-6, GCET-1, FOXP1 and Ki-67. The phenotypic classifications were assessed according to the standard of Hans model and Chan model. Data were analyzed by χ(2) test and Life Table survival analysis with the SPSS14.0 statistical package.
The ratio of male to female in this cohort was 1.26:1. The median age of all patients was 57 yrs with the average age of 53.5 yrs. Of 61 cases (33.7%) primarily showed lymph node involvement. Gastrointestinal tract as</description><identifier>ISSN: 0253-2727</identifier><identifier>PMID: 23384897</identifier><language>chi</language><publisher>China</publisher><subject>Adolescent ; Adult ; Aged ; Aged, 80 and over ; Algorithms ; Asian Continental Ancestry Group ; Child ; Child, Preschool ; Female ; Humans ; Lymphoma, Large B-Cell, Diffuse - classification ; Lymphoma, Large B-Cell, Diffuse - diagnosis ; Lymphoma, Large B-Cell, Diffuse - pathology ; Male ; Middle Aged ; Models, Theoretical ; Prognosis ; Young Adult</subject><ispartof>Zhōnghuá xuèyèxué zázhì, 2012-10, Vol.33 (10), p.801-804</ispartof><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23384897$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Li, Min</creatorcontrib><creatorcontrib>Liu, Cui-ling</creatorcontrib><creatorcontrib>Yin, Wen-juan</creatorcontrib><creatorcontrib>He, Yao-xin</creatorcontrib><creatorcontrib>Xue, Xue-min</creatorcontrib><creatorcontrib>Duan, Ze-jun</creatorcontrib><creatorcontrib>Gao, Zi-fen</creatorcontrib><title>The clinical significance of a new classification algorithm in Chinese DLBCL cases</title><title>Zhōnghuá xuèyèxué zázhì</title><addtitle>Zhonghua Xue Ye Xue Za Zhi</addtitle><description>To investigate the clinicopathologic features, pathogenesis, diagnostic criteria and the relationship between different classification models and prognosis in Chinese patients with DLBCL, and try to look for the most appropriate classification model to predict clinical prognosis and therapeutic responses for Chinese patients with DLBCL.
181 cases of Chinese DLBCLs diagnosed according to the WHO 2008 classification were collected. Standard two-step Envision method of immunohistochemical staining was used to assess the expressions of CD20, CD3ε, CD79a, CD10, Mum-1, Bcl-6, GCET-1, FOXP1 and Ki-67. The phenotypic classifications were assessed according to the standard of Hans model and Chan model. Data were analyzed by χ(2) test and Life Table survival analysis with the SPSS14.0 statistical package.
The ratio of male to female in this cohort was 1.26:1. The median age of all patients was 57 yrs with the average age of 53.5 yrs. Of 61 cases (33.7%) primarily showed lymph node involvement. Gastrointestinal tract as</description><subject>Adolescent</subject><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Algorithms</subject><subject>Asian Continental Ancestry Group</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Female</subject><subject>Humans</subject><subject>Lymphoma, Large B-Cell, Diffuse - classification</subject><subject>Lymphoma, Large B-Cell, Diffuse - diagnosis</subject><subject>Lymphoma, Large B-Cell, Diffuse - pathology</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Models, Theoretical</subject><subject>Prognosis</subject><subject>Young Adult</subject><issn>0253-2727</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo1UE1LxDAUzEFxl3X_guTopdC-13z0qPUTCoKs55Kkr9tAm65Ni_jvrbgyhxlmhjnMBdumIDABBWrD9jF6m4oMpUZMr9gGEHWuC7Vl74eOuOt98M70PPpj8O0qgyM-ttzwQF9rbNaBX3v2Y-CmP46Tn7uB-8DLzgeKxB-q-7LizkSK1-yyNX2k_Zl37OPp8VC-JNXb82t5VyWnDOSctEhtA-gya5sWhbPYFCANIqCAFbnUIEEhpMZoymQurLZaCqeaTBdEuGO3f7unafxcKM714KOjvjeBxiXWGWiR6lQVaq3enKuLHaipT5MfzPRd__-AP2xnWDM</recordid><startdate>201210</startdate><enddate>201210</enddate><creator>Li, Min</creator><creator>Liu, Cui-ling</creator><creator>Yin, Wen-juan</creator><creator>He, Yao-xin</creator><creator>Xue, Xue-min</creator><creator>Duan, Ze-jun</creator><creator>Gao, Zi-fen</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>201210</creationdate><title>The clinical significance of a new classification algorithm in Chinese DLBCL cases</title><author>Li, Min ; Liu, Cui-ling ; Yin, Wen-juan ; He, Yao-xin ; Xue, Xue-min ; Duan, Ze-jun ; Gao, Zi-fen</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p126t-f3efd23c1bbdf35cb3d926a3323525254682627320aa8e1645b8b865c7d189ee3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>chi</language><creationdate>2012</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Algorithms</topic><topic>Asian Continental Ancestry Group</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>Female</topic><topic>Humans</topic><topic>Lymphoma, Large B-Cell, Diffuse - classification</topic><topic>Lymphoma, Large B-Cell, Diffuse - diagnosis</topic><topic>Lymphoma, Large B-Cell, Diffuse - pathology</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Models, Theoretical</topic><topic>Prognosis</topic><topic>Young Adult</topic><toplevel>online_resources</toplevel><creatorcontrib>Li, Min</creatorcontrib><creatorcontrib>Liu, Cui-ling</creatorcontrib><creatorcontrib>Yin, Wen-juan</creatorcontrib><creatorcontrib>He, Yao-xin</creatorcontrib><creatorcontrib>Xue, Xue-min</creatorcontrib><creatorcontrib>Duan, Ze-jun</creatorcontrib><creatorcontrib>Gao, Zi-fen</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Zhōnghuá xuèyèxué zázhì</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Li, Min</au><au>Liu, Cui-ling</au><au>Yin, Wen-juan</au><au>He, Yao-xin</au><au>Xue, Xue-min</au><au>Duan, Ze-jun</au><au>Gao, Zi-fen</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The clinical significance of a new classification algorithm in Chinese DLBCL cases</atitle><jtitle>Zhōnghuá xuèyèxué zázhì</jtitle><addtitle>Zhonghua Xue Ye Xue Za Zhi</addtitle><date>2012-10</date><risdate>2012</risdate><volume>33</volume><issue>10</issue><spage>801</spage><epage>804</epage><pages>801-804</pages><issn>0253-2727</issn><abstract>To investigate the clinicopathologic features, pathogenesis, diagnostic criteria and the relationship between different classification models and prognosis in Chinese patients with DLBCL, and try to look for the most appropriate classification model to predict clinical prognosis and therapeutic responses for Chinese patients with DLBCL.
181 cases of Chinese DLBCLs diagnosed according to the WHO 2008 classification were collected. Standard two-step Envision method of immunohistochemical staining was used to assess the expressions of CD20, CD3ε, CD79a, CD10, Mum-1, Bcl-6, GCET-1, FOXP1 and Ki-67. The phenotypic classifications were assessed according to the standard of Hans model and Chan model. Data were analyzed by χ(2) test and Life Table survival analysis with the SPSS14.0 statistical package.
The ratio of male to female in this cohort was 1.26:1. The median age of all patients was 57 yrs with the average age of 53.5 yrs. Of 61 cases (33.7%) primarily showed lymph node involvement. Gastrointestinal tract as</abstract><cop>China</cop><pmid>23384897</pmid><tpages>4</tpages></addata></record> |
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| source | MEDLINE; EZB-FREE-00999 freely available EZB journals |
| subjects | Adolescent Adult Aged Aged, 80 and over Algorithms Asian Continental Ancestry Group Child Child, Preschool Female Humans Lymphoma, Large B-Cell, Diffuse - classification Lymphoma, Large B-Cell, Diffuse - diagnosis Lymphoma, Large B-Cell, Diffuse - pathology Male Middle Aged Models, Theoretical Prognosis Young Adult |
| title | The clinical significance of a new classification algorithm in Chinese DLBCL cases |
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