Protective Effect of K201 on Isoproterenol-Induced and Ischemic–Reperfusion-Induced Ventricular Arrhythmias in the Rat: Comparison With Diltiazem

Aim:Ventricular arrhythmia (VA) is a risk for sudden death. Polymorphic ventricular tachycardia (VT) degenerating to ventricular fibrillation occurs subsequent to the prolongation of the QT interval following administration of catecholamines under Ca2+ loading. Fatal VA also occurs in ischemia and i...

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Veröffentlicht in:	Journal of cardiovascular pharmacology and therapeutics 2013-03, Vol.18 (2), p.184-190
Hauptverfasser:	Otani, Naoyuki, Matsuda, Ryuko, Oda, Kazuhiko, Nishino, Setsu, Inoue, Teruo, Kaneko, Noboru
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Arrhythmias, Cardiac - chemically induced Arrhythmias, Cardiac - physiopathology Arrhythmias, Cardiac - prevention & control Cardiotonic Agents - therapeutic use Diltiazem - therapeutic use Isoproterenol - toxicity Male Myocardial Reperfusion Injury - chemically induced Myocardial Reperfusion Injury - physiopathology Myocardial Reperfusion Injury - prevention & control Rats Rats, Wistar Thiazepines - therapeutic use
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