Right-ventricular failure following left ventricle assist device implantation
PURPOSE OF REVIEWTo review recent insights on right-ventricular failure (RVF) following left-ventricular assist device (LVAD) implantation. RECENT FINDINGSEven with the availability of new generation continuous mechanical assist devices, RVF after implantation of LVAD is still associated with high m...
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Veröffentlicht in: | Current opinion in cardiology 2013-03, Vol.28 (2), p.223-233 |
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creator | Patlolla, Bhagat Beygui, Ramin Haddad, Francois |
description | PURPOSE OF REVIEWTo review recent insights on right-ventricular failure (RVF) following left-ventricular assist device (LVAD) implantation.
RECENT FINDINGSEven with the availability of new generation continuous mechanical assist devices, RVF after implantation of LVAD is still associated with high morbidity and mortality. Recent studies have tried to better define the risk of RVF using combined clinical scores and measures of right-ventricular function or strain. Small exploratory studies have also investigated the role of pulmonary vasodilators and phosphodiesterase inhibitors in selected patients receiving LVAD implantation.
SUMMARYMeasure of right-ventricular function could improve the risk stratification of RVF following LVAD implantation. Future multicenter studies are needed to validate right-ventricular risk scores and to develop evidence-guided preventive and therapeutic strategies. |
doi_str_mv | 10.1097/HCO.0b013e32835dd12c |
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RECENT FINDINGSEven with the availability of new generation continuous mechanical assist devices, RVF after implantation of LVAD is still associated with high morbidity and mortality. Recent studies have tried to better define the risk of RVF using combined clinical scores and measures of right-ventricular function or strain. Small exploratory studies have also investigated the role of pulmonary vasodilators and phosphodiesterase inhibitors in selected patients receiving LVAD implantation.
SUMMARYMeasure of right-ventricular function could improve the risk stratification of RVF following LVAD implantation. Future multicenter studies are needed to validate right-ventricular risk scores and to develop evidence-guided preventive and therapeutic strategies.</description><identifier>ISSN: 0268-4705</identifier><identifier>EISSN: 1531-7080</identifier><identifier>DOI: 10.1097/HCO.0b013e32835dd12c</identifier><identifier>PMID: 23337895</identifier><language>eng</language><publisher>United States: Lippincott Williams & Wilkins, Inc</publisher><subject>Cardiopulmonary Bypass - adverse effects ; Heart Failure - therapy ; Heart-Assist Devices - adverse effects ; Humans ; Multiple Organ Failure - epidemiology ; Multiple Organ Failure - physiopathology ; Risk Factors ; Ultrasonography ; Ventricular Dysfunction, Right - classification ; Ventricular Dysfunction, Right - diagnostic imaging ; Ventricular Dysfunction, Right - etiology ; Ventricular Dysfunction, Right - physiopathology</subject><ispartof>Current opinion in cardiology, 2013-03, Vol.28 (2), p.223-233</ispartof><rights>2013 Lippincott Williams & Wilkins, Inc.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c422c-c34d1c1b273b4d4d53feb35965eee2590baa9f06af570ee35233c126b45e23063</citedby><cites>FETCH-LOGICAL-c422c-c34d1c1b273b4d4d53feb35965eee2590baa9f06af570ee35233c126b45e23063</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23337895$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Patlolla, Bhagat</creatorcontrib><creatorcontrib>Beygui, Ramin</creatorcontrib><creatorcontrib>Haddad, Francois</creatorcontrib><title>Right-ventricular failure following left ventricle assist device implantation</title><title>Current opinion in cardiology</title><addtitle>Curr Opin Cardiol</addtitle><description>PURPOSE OF REVIEWTo review recent insights on right-ventricular failure (RVF) following left-ventricular assist device (LVAD) implantation.
RECENT FINDINGSEven with the availability of new generation continuous mechanical assist devices, RVF after implantation of LVAD is still associated with high morbidity and mortality. Recent studies have tried to better define the risk of RVF using combined clinical scores and measures of right-ventricular function or strain. Small exploratory studies have also investigated the role of pulmonary vasodilators and phosphodiesterase inhibitors in selected patients receiving LVAD implantation.
SUMMARYMeasure of right-ventricular function could improve the risk stratification of RVF following LVAD implantation. Future multicenter studies are needed to validate right-ventricular risk scores and to develop evidence-guided preventive and therapeutic strategies.</description><subject>Cardiopulmonary Bypass - adverse effects</subject><subject>Heart Failure - therapy</subject><subject>Heart-Assist Devices - adverse effects</subject><subject>Humans</subject><subject>Multiple Organ Failure - epidemiology</subject><subject>Multiple Organ Failure - physiopathology</subject><subject>Risk Factors</subject><subject>Ultrasonography</subject><subject>Ventricular Dysfunction, Right - classification</subject><subject>Ventricular Dysfunction, Right - diagnostic imaging</subject><subject>Ventricular Dysfunction, Right - etiology</subject><subject>Ventricular Dysfunction, Right - physiopathology</subject><issn>0268-4705</issn><issn>1531-7080</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kD1PwzAURS0EoqXwDxDKyJLiz8QZUQUUqagSgtlynJfW4CTFdlrx7wlqYWBgesu5910dhC4JnhJc5Dfz2XKKS0wYMCqZqCpCzREaE8FImmOJj9EY00ymPMdihM5CeMMY06LITtGIMsZyWYgxenq2q3VMt9BGb03vtE9qbV3vIak757qdbVeJgzomB8RBokOwISYVbK2BxDYbp9uoo-3ac3RSaxfg4nAn6PX-7mU2TxfLh8fZ7SI1nFKTGsYrYkhJc1byileC1VAyUWQCAKgocKl1UeNM1yLHAEwMew2hWckFUIYzNkHX-96N7z56CFE1NhhwwxDo-qAIlTyjTEoyoHyPGt-F4KFWG28b7T8VwepbpBpEqr8ih9jV4UNfNlD9hn7MDYDcA7vORfDh3fU78GoN2sX1_91f1SqDHw</recordid><startdate>201303</startdate><enddate>201303</enddate><creator>Patlolla, Bhagat</creator><creator>Beygui, Ramin</creator><creator>Haddad, Francois</creator><general>Lippincott Williams & Wilkins, Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>201303</creationdate><title>Right-ventricular failure following left ventricle assist device implantation</title><author>Patlolla, Bhagat ; Beygui, Ramin ; Haddad, Francois</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c422c-c34d1c1b273b4d4d53feb35965eee2590baa9f06af570ee35233c126b45e23063</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>Cardiopulmonary Bypass - adverse effects</topic><topic>Heart Failure - therapy</topic><topic>Heart-Assist Devices - adverse effects</topic><topic>Humans</topic><topic>Multiple Organ Failure - epidemiology</topic><topic>Multiple Organ Failure - physiopathology</topic><topic>Risk Factors</topic><topic>Ultrasonography</topic><topic>Ventricular Dysfunction, Right - classification</topic><topic>Ventricular Dysfunction, Right - diagnostic imaging</topic><topic>Ventricular Dysfunction, Right - etiology</topic><topic>Ventricular Dysfunction, Right - physiopathology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Patlolla, Bhagat</creatorcontrib><creatorcontrib>Beygui, Ramin</creatorcontrib><creatorcontrib>Haddad, Francois</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Current opinion in cardiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Patlolla, Bhagat</au><au>Beygui, Ramin</au><au>Haddad, Francois</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Right-ventricular failure following left ventricle assist device implantation</atitle><jtitle>Current opinion in cardiology</jtitle><addtitle>Curr Opin Cardiol</addtitle><date>2013-03</date><risdate>2013</risdate><volume>28</volume><issue>2</issue><spage>223</spage><epage>233</epage><pages>223-233</pages><issn>0268-4705</issn><eissn>1531-7080</eissn><abstract>PURPOSE OF REVIEWTo review recent insights on right-ventricular failure (RVF) following left-ventricular assist device (LVAD) implantation.
RECENT FINDINGSEven with the availability of new generation continuous mechanical assist devices, RVF after implantation of LVAD is still associated with high morbidity and mortality. Recent studies have tried to better define the risk of RVF using combined clinical scores and measures of right-ventricular function or strain. Small exploratory studies have also investigated the role of pulmonary vasodilators and phosphodiesterase inhibitors in selected patients receiving LVAD implantation.
SUMMARYMeasure of right-ventricular function could improve the risk stratification of RVF following LVAD implantation. Future multicenter studies are needed to validate right-ventricular risk scores and to develop evidence-guided preventive and therapeutic strategies.</abstract><cop>United States</cop><pub>Lippincott Williams & Wilkins, Inc</pub><pmid>23337895</pmid><doi>10.1097/HCO.0b013e32835dd12c</doi><tpages>11</tpages></addata></record> |
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subjects | Cardiopulmonary Bypass - adverse effects Heart Failure - therapy Heart-Assist Devices - adverse effects Humans Multiple Organ Failure - epidemiology Multiple Organ Failure - physiopathology Risk Factors Ultrasonography Ventricular Dysfunction, Right - classification Ventricular Dysfunction, Right - diagnostic imaging Ventricular Dysfunction, Right - etiology Ventricular Dysfunction, Right - physiopathology |
title | Right-ventricular failure following left ventricle assist device implantation |
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