Airway contractility and remodeling: Links to asthma symptoms

Abstract Respiratory symptoms are largely caused by obstruction of the airways. In asthma, airway narrowing mediated by airway smooth muscle (ASM) contraction contributes significantly to obstruction. The spasmogens produced following exposure to environmental triggers, such as viruses or allergens,...

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Veröffentlicht in:	Pulmonary pharmacology & therapeutics 2013-02, Vol.26 (1), p.3-12
Hauptverfasser:	West, Adrian R, Syyong, Harley T, Siddiqui, Sana, Pascoe, Chris D, Murphy, Thomas M, Maarsingh, Harm, Deng, Linhong, Maksym, Geoffrey N, Bossé, Ynuk
Format:	Artikel
Sprache:	eng
Schlagworte:	Airway hyperresponsiveness Airway Obstruction - physiopathology Airway Remodeling - physiology Airway smooth muscle Animals Asthma Asthma - physiopathology Bronchial Hyperreactivity - physiopathology Contractility Humans Medical Education Muscle, Smooth - metabolism Pulmonary/Respiratory Remodeling Respiratory Function Tests Spasmogens Tone
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