Construction of alpha -amido-indanones viaformal allenamide hydroacylation-Nazarov cyclization

A two-step modular synthesis of an alpha -hydroxycyclopentenone and alpha -amido-indanones has been developed based on the Nazarov cyclization of 2-amido-1,4-pentadien-3-ones, readily accessed viaformal hydroacylation of allenamides.

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Veröffentlicht in:Chemical communications (Cambridge, England) England), 2012-08, Vol.48 (73), p.9186-9188
Hauptverfasser: Wu, Yen-Ku, Niu, Tianmin, West, F G
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container_title Chemical communications (Cambridge, England)
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creator Wu, Yen-Ku
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West, F G
description A two-step modular synthesis of an alpha -hydroxycyclopentenone and alpha -amido-indanones has been developed based on the Nazarov cyclization of 2-amido-1,4-pentadien-3-ones, readily accessed viaformal hydroacylation of allenamides.
doi_str_mv 10.1039/c2cc34644c
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source Royal Society Of Chemistry Journals 2008-; Alma/SFX Local Collection
subjects Construction
Modular
Synthesis
title Construction of alpha -amido-indanones viaformal allenamide hydroacylation-Nazarov cyclization
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