Cardiac mitochondrial dysfunction during hyperglycemiaaThe role of oxidative stress and p66Shc signaling

Diabetes mellitus is a chronic disease caused by a deficiency in the production of insulin and/or by the effects of insulin resistance. Insulin deficiency leads to hyperglycemia which is the major initiator of diabetic cardiovascular complications escalating with time and driven by many complex bioc...

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Veröffentlicht in:	The international journal of biochemistry & cell biology 2013-01, Vol.45 (1), p.114-122
Hauptverfasser:	Diogo, Catia V, Suski, Jan M, Lebiedzinska, Magdalena, Karkucinska-Wieckowska, Agnieszka, Wojtala, Aleksandra, Pronicki, Maciej, Duszynski, Jerzy, Pinton, Paolo, Portincasa, Piero, Oliveira, Paulo J, Wieckowski, Mariusz R
Format:	Artikel
Sprache:	eng
Schlagworte:	Biochemistry Biology Flux Impairment Insulin Kinases Pathways Polyols
Online-Zugang:	Volltext
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