Spontaneously formed semipermeable organic-inorganic hybrid vesicles permitting molecular weight selective transmembrane passage

Semipermeable organic-inorganic hybrid vesicles coated with a siloxane surface were spontaneously formed by simple dispersion of an organoalkoxysilane lipid in water. The hybrid vesicles allow the permeation of hydrophilic small molecules across the membrane without an introduction of a pore-forming...

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Veröffentlicht in:Chemical communications (Cambridge, England) England), 2013-01, Vol.49 (7), p.665-667
Hauptverfasser: Yasuhara, Kazuma, Kawataki, Takahiro, Okuda, Shizuyo, Oshima, Shohei, Kikuchi, Jun-ichi
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container_issue 7
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container_title Chemical communications (Cambridge, England)
container_volume 49
creator Yasuhara, Kazuma
Kawataki, Takahiro
Okuda, Shizuyo
Oshima, Shohei
Kikuchi, Jun-ichi
description Semipermeable organic-inorganic hybrid vesicles coated with a siloxane surface were spontaneously formed by simple dispersion of an organoalkoxysilane lipid in water. The hybrid vesicles allow the permeation of hydrophilic small molecules across the membrane without an introduction of a pore-forming protein.
doi_str_mv 10.1039/c2cc36662b
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source MEDLINE; Royal Society Of Chemistry Journals 2008-; Alma/SFX Local Collection
subjects Alanine - analogs & derivatives
Alanine - chemical synthesis
Dispersions
Hydrophobic and Hydrophilic Interactions
Lipids
Membranes, Artificial
Molecular Weight
Penetration
Permeability
Permeation
Proteins
Siloxanes
Siloxanes - chemistry
Vesicles
title Spontaneously formed semipermeable organic-inorganic hybrid vesicles permitting molecular weight selective transmembrane passage
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