Estimation of cell density to aid in assessment of percentage cells of a particular lineage or of cells expressing a specific antigen in bone marrow trephine biopsies

The authors aimed to develop a tool to assess total cell numbers in a microscope's field of vision, which would provide the denominator for calculating the percentage of positive cells for a given antigen in bone marrow trephine biopsies (BMTBs) of varying cellularities. Precise estimates of ce...

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Veröffentlicht in:	Journal of clinical pathology 2013-02, Vol.66 (2), p.155-159
Hauptverfasser:	Al-Shieban, Saeed, Tadrous, Paul J, Naresh, Kikkeri N
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Aged, 80 and over Antigens Antigens - analysis Biomarkers - analysis Biopsy Biopsy - instrumentation Bone marrow Bone Marrow Cells - immunology Bone Marrow Examination bone marrow trephines Cell Count Cell counting Cell Lineage Child Child, Preschool colorectal cancer erythrocyte Estimates Female gall bladder haemato-oncology haematology Hematology Hodgkin's disease Humans immunohistochemistry Infant leukaemia lymphoma Male MALT-lymphoma Microscopy Middle Aged myeloproliferative disease oncogenes p53 pancreas polycythaemia Predictive Value of Tests Reproducibility of Results Trephining - instrumentation Validation studies virology Young Adult
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