Aurora A kinase (AURKA) in normal and pathological cell division

Temporally and spatially controlled activation of the Aurora A kinase (AURKA) regulates centrosome maturation, entry into mitosis, formation and function of the bipolar spindle, and cytokinesis. Genetic amplification and mRNA and protein overexpression of Aurora A are common in many types of solid t...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Cellular and molecular life sciences : CMLS 2013-02, Vol.70 (4), p.661-687
Hauptverfasser:	Nikonova, Anna S., Astsaturov, Igor, Serebriiskii, Ilya G., Dunbrack, Roland L., Golemis, Erica A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Aurora Kinase A Aurora Kinases Biochemistry Biomedical and Life Sciences Biomedicine Cancer Cell Biology Cell cycle Cell Division Enzyme Activation Enzyme Inhibitors - pharmacology Enzyme Inhibitors - therapeutic use Gene expression Gene Expression Regulation, Neoplastic Humans Kinases Life Sciences Models, Molecular Neoplasms - drug therapy Neoplasms - enzymology Neoplasms - genetics Neoplasms - metabolism Pathology Protein Conformation Protein Interaction Maps Protein Serine-Threonine Kinases - antagonists & inhibitors Protein Serine-Threonine Kinases - chemistry Protein Serine-Threonine Kinases - genetics Protein Serine-Threonine Kinases - metabolism Proteins Review Tumors
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!