Kefir inhibits 3T3-L1 adipocyte differentiation through down-regulation of adipogenic transcription factor expression

BACKGROUND: Kefir, a traditional fermented milk composed of microbial symbionts, is reported to have various health benefits such as anti‐tumour, anti‐inflammatory, anti‐neoplastic and pro‐digestive effects. In this study, to elucidate the effects of kefir on adipocyte differentiation and lipid accu...

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Veröffentlicht in:	Journal of the science of food and agriculture 2013-02, Vol.93 (3), p.485-490
Hauptverfasser:	Ho, Jin-Nyoung, Choi, Jae-Woo, Lim, Won-Chul, Kim, Mi-Kyoung, Lee, In-Young, Cho, Hong-Yon
Format:	Artikel
Sprache:	eng
Schlagworte:	3T3-L1 Cells Adipocytes - cytology Adipogenesis - genetics Animals C/EBPα CCAAT-Enhancer-Binding Protein-alpha - antagonists & inhibitors CCAAT-Enhancer-Binding Protein-alpha - genetics Cell Differentiation - physiology Cells Cultured Milk Products - chemistry Cultured Milk Products - physiology Down-Regulation Fermentation Food science Gene expression glycerol-3-phosphate dehydrogenase (GPDH) Glycerolphosphate Dehydrogenase - antagonists & inhibitors kefir Lipids Mice Milk PPAR gamma - antagonists & inhibitors PPAR gamma - genetics PPARγ RNA, Messenger - genetics Solubility SREBP-1c Sterol Regulatory Element Binding Protein 1 - antagonists & inhibitors Sterol Regulatory Element Binding Protein 1 - genetics Transcription Factors - genetics
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