Plasticity within the αβ+CD4+ T-cell lineage: when, how and what for?

Following thymic output, αβ+CD4+ T cells become activated in the periphery when they encounter peptide–major histocompatibility complex. A combination of cytokine and co-stimulatory signals instructs the differentiation of T cells into various lineages and subsequent expansion and contraction during...

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Veröffentlicht in:	Open biology 2013, Vol.3 (1), p.120157-120157
Hauptverfasser:	Coomes, Stephanie M., Pelly, Victoria S., Wilson, Mark S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals CD4-Positive T-Lymphocytes - cytology CD4-Positive T-Lymphocytes - immunology Cell Lineage - immunology Humans Infection Review T Helper Cell T Regulatory Cell T-Lymphocytes, Helper-Inducer - cytology T-Lymphocytes, Helper-Inducer - immunology T-Lymphocytes, Regulatory - cytology T-Lymphocytes, Regulatory - immunology
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