Effect of Valsartan on Systemic Right Ventricular Function: A Double-Blind, Randomized, Placebo-Controlled Pilot Trial

The role of angiotensin II receptor blockers in patients with a systemic right ventricle has not been elucidated. We conducted a multicenter, double-blind, parallel, randomized controlled trial of angiotensin II receptor blocker valsartan 160 mg twice daily compared with placebo in patients with a s...

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Veröffentlicht in:	Circulation (New York, N.Y.) N.Y.), 2013-01, Vol.127 (3), p.322-330
Hauptverfasser:	VAN DER BOM, Teun, WINTER, Michiel M, MULDER, Barbara J. M, BOUMA, Berto J, GROENINK, Maarten, VLIEGEN, Hubert W, PIEPER, Petronella G, VAN DIJK, Arie P. J, SIESWERDA, Gertjan T, ROOS-HESSELINK, Jolien W, ZWINDERMAN, Aeilko H
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Angiotensin II Type 1 Receptor Blockers - adverse effects Angiotensin II Type 1 Receptor Blockers - pharmacology Angiotensin II Type 1 Receptor Blockers - therapeutic use Biological and medical sciences Blood and lymphatic vessels Cardiology. Vascular system Cardiovascular system Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous Double-Blind Method Exercise Tolerance - drug effects Exercise Tolerance - physiology Female Follow-Up Studies Heart Defects, Congenital - complications Heart Ventricles - drug effects Heart Ventricles - physiopathology Humans Magnetic Resonance Imaging Male Medical sciences Multidetector Computed Tomography Outcome Assessment (Health Care) Pharmacology. Drug treatments Pilot Projects Quality of Life Stroke Volume - drug effects Stroke Volume - physiology Tetrazoles - adverse effects Tetrazoles - pharmacology Tetrazoles - therapeutic use Transposition of Great Vessels - complications Valine - adverse effects Valine - analogs & derivatives Valine - pharmacology Valine - therapeutic use Valsartan Vasodilator agents. Cerebral vasodilators Ventricular Dysfunction, Right - drug therapy Ventricular Dysfunction, Right - etiology Ventricular Dysfunction, Right - physiopathology
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