Hydrogen sulfide inhibits preoptic prostaglandin E2 production during endotoxemia

Hydrogen sulfide (H2S) is a gaseous neuromodulator endogenously produced in the brain by the enzyme cystathionine β-synthase (CBS). We tested the hypothesis that H2S acts within the anteroventral preoptic region of the hypothalamus (AVPO) modulating the production of prostaglandin (PG) E2 (the proxi...

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Veröffentlicht in:	Experimental neurology 2013-02, Vol.240, p.88-95
Hauptverfasser:	Kwiatkoski, Marcelo, Soriano, Renato N., Araujo, Rebeca M., Azevedo, Leopoldo U., Batalhao, Marcelo E., Francescato, Heloísa D.C., Coimbra, Terezila M., Carnio, Evelin C., Branco, Luiz G.S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aminooxyacetate Animals Anteroventral preoptic region of the hypothalamus Biological and medical sciences Cyclic adenosine monophosphate Cystathionine β-synthase Dinoprostone - biosynthesis Dinoprostone - metabolism Disease Models, Animal Endotoxemia - chemically induced Endotoxemia - metabolism Endotoxin Fever Fever - chemically induced Fever - metabolism Hydrogen sulfide Hydrogen Sulfide - metabolism Hydrogen Sulfide - pharmacology Lipopolysaccharide Male Medical sciences Multiple sclerosis and variants. Guillain barré syndrome and other inflammatory polyneuropathies. Leukoencephalitis Neurology Preoptic Area - metabolism Prostaglandin E2 Rats Rats, Wistar Systemic inflammation
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