Plasma concentrations of the vitamin E-binding protein afamin are associated with overall and progression-free survival and platinum sensitivity in serous ovarian cancer—a study by the OVCAD consortium

Abstract Objective Comparative proteomics identified the plasma protein afamin as potential biomarker for ovarian cancer (OC). Significantly decreased afamin plasma concentrations in pre-therapeutic OC patients reconstituted to control values after successful tumor surgery. This study evaluates the...

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Veröffentlicht in:	Gynecologic oncology 2013-01, Vol.128 (1), p.38-43
Hauptverfasser:	Melmer, Andreas, Fineder, Linda, Lamina, Claudia, Kollerits, Barbara, Dieplinger, Benjamin, Braicu, Ioana, Sehouli, Jalid, Cadron, Isabelle, Vergote, Ignace, Mahner, Sven, Zeimet, Alain G, Castillo-Tong, Dan Cacsire, Ebenbichler, Christoph F, Zeillinger, Robert, Dieplinger, Hans
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Afamin Aged Aged, 80 and over Antineoplastic Combined Chemotherapy Protocols - administration & dosage Antineoplastic Combined Chemotherapy Protocols - therapeutic use CA-125 Antigen - blood Carrier Proteins - blood Cystadenocarcinoma, Serous - blood Cystadenocarcinoma, Serous - drug therapy Cystadenocarcinoma, Serous - mortality Cystadenocarcinoma, Serous - pathology Female Glycoproteins - blood Hematology, Oncology and Palliative Medicine Humans Middle Aged Neoplasm Staging Obstetrics and Gynecology Organoplatinum Compounds - administration & dosage Organoplatinum Compounds - pharmacology Organoplatinum Compounds - therapeutic use Ovarian cancer Ovarian Neoplasms - blood Ovarian Neoplasms - drug therapy Ovarian Neoplasms - mortality Ovarian Neoplasms - pathology Proportional Hazards Models Response to therapy Serum Albumin Serum Albumin, Human Survival statistics Translational research Tumor marker
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