Noise-based tube current reduction method with iterative reconstruction for reduction of radiation exposure in coronary CT angiography
Abstract Purpose To investigate the potential of noise-based tube current reduction method with iterative reconstruction to reduce radiation exposure while achieving consistent image quality in coronary CT angiography (CCTA). Materials and methods 294 patients underwent CCTA on a 64-detector row CT...
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Veröffentlicht in: | European journal of radiology 2013-02, Vol.82 (2), p.349-355 |
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description | Abstract Purpose To investigate the potential of noise-based tube current reduction method with iterative reconstruction to reduce radiation exposure while achieving consistent image quality in coronary CT angiography (CCTA). Materials and methods 294 patients underwent CCTA on a 64-detector row CT equipped with iterative reconstruction. 102 patients with fixed tube current were assigned to Group 1, which was used to establish noise-based tube current modulation formulas, where tube current was modulated by the noise of test bolus image. 192 patients with noise-based tube current were randomly assigned to Group 2 and Group 3. Filtered back projection was applied for Group 2 and iterative reconstruction for Group 3. Qualitative image quality was assessed with a 5 point score. Image noise, signal intensity, volume CT dose index, and dose-length product were measured. Results The noise-based tube current modulation formulas were established through regression analysis using image noise measurements in Group 1. Image noise was precisely maintained at the target value of 35.00 HU with small interquartile ranges for Group 2 (34.17–35.08 HU) and Group 3 (34.34–35.03 HU), while it was from 28.41 to 36.49 HU for Group 1. All images in the three groups were acceptable for diagnosis. A relative 14% and 41% reduction in effective dose for Group 2 and Group 3 were observed compared with Group 1. Conclusion Adequate image quality could be maintained at a desired and consistent noise level with overall 14% dose reduction using noise-based tube current reduction method. The use of iterative reconstruction further achieved approximately 40% reduction in effective dose. |
doi_str_mv | 10.1016/j.ejrad.2012.10.008 |
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Materials and methods 294 patients underwent CCTA on a 64-detector row CT equipped with iterative reconstruction. 102 patients with fixed tube current were assigned to Group 1, which was used to establish noise-based tube current modulation formulas, where tube current was modulated by the noise of test bolus image. 192 patients with noise-based tube current were randomly assigned to Group 2 and Group 3. Filtered back projection was applied for Group 2 and iterative reconstruction for Group 3. Qualitative image quality was assessed with a 5 point score. Image noise, signal intensity, volume CT dose index, and dose-length product were measured. Results The noise-based tube current modulation formulas were established through regression analysis using image noise measurements in Group 1. Image noise was precisely maintained at the target value of 35.00 HU with small interquartile ranges for Group 2 (34.17–35.08 HU) and Group 3 (34.34–35.03 HU), while it was from 28.41 to 36.49 HU for Group 1. All images in the three groups were acceptable for diagnosis. A relative 14% and 41% reduction in effective dose for Group 2 and Group 3 were observed compared with Group 1. Conclusion Adequate image quality could be maintained at a desired and consistent noise level with overall 14% dose reduction using noise-based tube current reduction method. The use of iterative reconstruction further achieved approximately 40% reduction in effective dose.</description><identifier>ISSN: 0720-048X</identifier><identifier>EISSN: 1872-7727</identifier><identifier>DOI: 10.1016/j.ejrad.2012.10.008</identifier><identifier>PMID: 23140592</identifier><language>eng</language><publisher>Ireland: Elsevier Ireland Ltd</publisher><subject>Adult ; Aged ; Aged, 80 and over ; Body Burden ; Coronary Angiography - methods ; Coronary Artery Disease - diagnostic imaging ; Coronary CT angiography ; Feasibility Studies ; Female ; Humans ; Image Enhancement - methods ; Image Interpretation, Computer-Assisted - methods ; Iterative reconstruction ; Male ; Middle Aged ; Radiation Dosage ; Radiation dose ; Radiation Protection - methods ; Radiology ; Reproducibility of Results ; Sensitivity and Specificity ; Signal-To-Noise Ratio ; Tomography, X-Ray Computed - methods</subject><ispartof>European journal of radiology, 2013-02, Vol.82 (2), p.349-355</ispartof><rights>Elsevier Ireland Ltd</rights><rights>2012 Elsevier Ireland Ltd</rights><rights>Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c459t-3353b27532afecfaae5df45d424074c71208e11e5302befeb43a459ad04f133c3</citedby><cites>FETCH-LOGICAL-c459t-3353b27532afecfaae5df45d424074c71208e11e5302befeb43a459ad04f133c3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.ejrad.2012.10.008$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23140592$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Shen, Junlin</creatorcontrib><creatorcontrib>Du, Xiangying</creatorcontrib><creatorcontrib>Guo, Daode</creatorcontrib><creatorcontrib>Cao, Lizhen</creatorcontrib><creatorcontrib>Gao, Yan</creatorcontrib><creatorcontrib>Bai, Mei</creatorcontrib><creatorcontrib>Li, Pengyu</creatorcontrib><creatorcontrib>Liu, Jiabin</creatorcontrib><creatorcontrib>Li, Kuncheng</creatorcontrib><title>Noise-based tube current reduction method with iterative reconstruction for reduction of radiation exposure in coronary CT angiography</title><title>European journal of radiology</title><addtitle>Eur J Radiol</addtitle><description>Abstract Purpose To investigate the potential of noise-based tube current reduction method with iterative reconstruction to reduce radiation exposure while achieving consistent image quality in coronary CT angiography (CCTA). Materials and methods 294 patients underwent CCTA on a 64-detector row CT equipped with iterative reconstruction. 102 patients with fixed tube current were assigned to Group 1, which was used to establish noise-based tube current modulation formulas, where tube current was modulated by the noise of test bolus image. 192 patients with noise-based tube current were randomly assigned to Group 2 and Group 3. Filtered back projection was applied for Group 2 and iterative reconstruction for Group 3. Qualitative image quality was assessed with a 5 point score. Image noise, signal intensity, volume CT dose index, and dose-length product were measured. Results The noise-based tube current modulation formulas were established through regression analysis using image noise measurements in Group 1. Image noise was precisely maintained at the target value of 35.00 HU with small interquartile ranges for Group 2 (34.17–35.08 HU) and Group 3 (34.34–35.03 HU), while it was from 28.41 to 36.49 HU for Group 1. All images in the three groups were acceptable for diagnosis. A relative 14% and 41% reduction in effective dose for Group 2 and Group 3 were observed compared with Group 1. Conclusion Adequate image quality could be maintained at a desired and consistent noise level with overall 14% dose reduction using noise-based tube current reduction method. The use of iterative reconstruction further achieved approximately 40% reduction in effective dose.</description><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Body Burden</subject><subject>Coronary Angiography - methods</subject><subject>Coronary Artery Disease - diagnostic imaging</subject><subject>Coronary CT angiography</subject><subject>Feasibility Studies</subject><subject>Female</subject><subject>Humans</subject><subject>Image Enhancement - methods</subject><subject>Image Interpretation, Computer-Assisted - methods</subject><subject>Iterative reconstruction</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Radiation Dosage</subject><subject>Radiation dose</subject><subject>Radiation Protection - methods</subject><subject>Radiology</subject><subject>Reproducibility of Results</subject><subject>Sensitivity and Specificity</subject><subject>Signal-To-Noise Ratio</subject><subject>Tomography, X-Ray Computed - methods</subject><issn>0720-048X</issn><issn>1872-7727</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFUk1vEzEQtRCIhsIvQEI-ctngr8WbA0go4kuq6KFF4mZ57XHjZWMH21vIH-B315sEhLj0NJrxezPj9wah55QsKaGvXw1LGJK2S0Yoq5UlId0DtKCdZI2UTD5ECyIZaYjovp2hJzkPhJBWrNhjdMY4FaRdsQX6_SX6DE2vM1hcph6wmVKCUHACO5niY8BbKJto8U9fNtgXSLr4W6jvJoZc0gnkYvqHEh2uq3l9SODXLuYpAfYBm5hi0GmP19dYhxsfb5LebfZP0SOnxwzPTvEcff3w_nr9qbm4_Ph5_e6iMaJdlYbzlvdMtpxpB8ZpDa11orWCCSKFkZSRDiiFlhPWg4NecF2J2hLhKOeGn6OXx767FH9MkIva-mxgHHWAOGVFmeRSCNaJCuVHqEkx5wRO7ZLf1tUVJWo2QA3qYICaDZiL1YDKenEaMPVbsH85fxSvgDdHANRv3npIKhsPwYD1VdGibPT3DHj7H9-MPnijx--whzzEKYWqoKIqM0XU1XwD8wnQQ5CU3wHlvbAs</recordid><startdate>20130201</startdate><enddate>20130201</enddate><creator>Shen, Junlin</creator><creator>Du, Xiangying</creator><creator>Guo, Daode</creator><creator>Cao, Lizhen</creator><creator>Gao, Yan</creator><creator>Bai, Mei</creator><creator>Li, Pengyu</creator><creator>Liu, Jiabin</creator><creator>Li, Kuncheng</creator><general>Elsevier Ireland Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20130201</creationdate><title>Noise-based tube current reduction method with iterative reconstruction for reduction of radiation exposure in coronary CT angiography</title><author>Shen, Junlin ; Du, Xiangying ; Guo, Daode ; Cao, Lizhen ; Gao, Yan ; Bai, Mei ; Li, Pengyu ; Liu, Jiabin ; Li, Kuncheng</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c459t-3353b27532afecfaae5df45d424074c71208e11e5302befeb43a459ad04f133c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Body Burden</topic><topic>Coronary Angiography - methods</topic><topic>Coronary Artery Disease - diagnostic imaging</topic><topic>Coronary CT angiography</topic><topic>Feasibility Studies</topic><topic>Female</topic><topic>Humans</topic><topic>Image Enhancement - methods</topic><topic>Image Interpretation, Computer-Assisted - methods</topic><topic>Iterative reconstruction</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Radiation Dosage</topic><topic>Radiation dose</topic><topic>Radiation Protection - methods</topic><topic>Radiology</topic><topic>Reproducibility of Results</topic><topic>Sensitivity and Specificity</topic><topic>Signal-To-Noise Ratio</topic><topic>Tomography, X-Ray Computed - methods</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Shen, Junlin</creatorcontrib><creatorcontrib>Du, Xiangying</creatorcontrib><creatorcontrib>Guo, Daode</creatorcontrib><creatorcontrib>Cao, Lizhen</creatorcontrib><creatorcontrib>Gao, Yan</creatorcontrib><creatorcontrib>Bai, Mei</creatorcontrib><creatorcontrib>Li, Pengyu</creatorcontrib><creatorcontrib>Liu, Jiabin</creatorcontrib><creatorcontrib>Li, Kuncheng</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>European journal of radiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Shen, Junlin</au><au>Du, Xiangying</au><au>Guo, Daode</au><au>Cao, Lizhen</au><au>Gao, Yan</au><au>Bai, Mei</au><au>Li, Pengyu</au><au>Liu, Jiabin</au><au>Li, Kuncheng</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Noise-based tube current reduction method with iterative reconstruction for reduction of radiation exposure in coronary CT angiography</atitle><jtitle>European journal of radiology</jtitle><addtitle>Eur J Radiol</addtitle><date>2013-02-01</date><risdate>2013</risdate><volume>82</volume><issue>2</issue><spage>349</spage><epage>355</epage><pages>349-355</pages><issn>0720-048X</issn><eissn>1872-7727</eissn><abstract>Abstract Purpose To investigate the potential of noise-based tube current reduction method with iterative reconstruction to reduce radiation exposure while achieving consistent image quality in coronary CT angiography (CCTA). Materials and methods 294 patients underwent CCTA on a 64-detector row CT equipped with iterative reconstruction. 102 patients with fixed tube current were assigned to Group 1, which was used to establish noise-based tube current modulation formulas, where tube current was modulated by the noise of test bolus image. 192 patients with noise-based tube current were randomly assigned to Group 2 and Group 3. Filtered back projection was applied for Group 2 and iterative reconstruction for Group 3. Qualitative image quality was assessed with a 5 point score. Image noise, signal intensity, volume CT dose index, and dose-length product were measured. Results The noise-based tube current modulation formulas were established through regression analysis using image noise measurements in Group 1. Image noise was precisely maintained at the target value of 35.00 HU with small interquartile ranges for Group 2 (34.17–35.08 HU) and Group 3 (34.34–35.03 HU), while it was from 28.41 to 36.49 HU for Group 1. All images in the three groups were acceptable for diagnosis. A relative 14% and 41% reduction in effective dose for Group 2 and Group 3 were observed compared with Group 1. Conclusion Adequate image quality could be maintained at a desired and consistent noise level with overall 14% dose reduction using noise-based tube current reduction method. The use of iterative reconstruction further achieved approximately 40% reduction in effective dose.</abstract><cop>Ireland</cop><pub>Elsevier Ireland Ltd</pub><pmid>23140592</pmid><doi>10.1016/j.ejrad.2012.10.008</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Adult Aged Aged, 80 and over Body Burden Coronary Angiography - methods Coronary Artery Disease - diagnostic imaging Coronary CT angiography Feasibility Studies Female Humans Image Enhancement - methods Image Interpretation, Computer-Assisted - methods Iterative reconstruction Male Middle Aged Radiation Dosage Radiation dose Radiation Protection - methods Radiology Reproducibility of Results Sensitivity and Specificity Signal-To-Noise Ratio Tomography, X-Ray Computed - methods |
title | Noise-based tube current reduction method with iterative reconstruction for reduction of radiation exposure in coronary CT angiography |
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