Up-regulation of microRNA-1290 impairs cytokinesis and affects the reprogramming of colon cancer cells

► miR-1290 is up-regulated in colon cancer cells. ► Up-regulation of miR-1290 impairs cytokinesis. ► miR-1290 overexpression affects the reprogramming of colon cancer cells. Abnormal cytokinesis increases the possibility of nuclear fusion in tumor cells. However, the role of microRNAs (miRNAs) in ab...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Cancer letters 2013-02, Vol.329 (2), p.155-163
Hauptverfasser:	Wu, Jia, Ji, Xiaowei, Zhu, Linlin, Jiang, Qiaoli, Wen, Zhenzhen, Xu, Song, Shao, Wei, Cai, Jianting, Du, Qin, Zhu, Yongliang, Mao, Jianshan
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenoma - genetics Adenoma - metabolism Adenoma - pathology Base Sequence Binding Sites Breast cancer Cell division Cell growth Cell Line, Tumor Cell Nucleus Division Cell Proliferation Chromosomes Colon cancer Colonic Neoplasms - genetics Colonic Neoplasms - metabolism Colonic Neoplasms - pathology Colorectal cancer colorectal neoplasms Cytokinesis Cytokinesis - genetics gene expression regulation Gene Expression Regulation, Neoplastic Hematology, Oncology and Palliative Medicine Homeodomain Proteins - metabolism Humans Hybridization KIF13B Kinases Kinesin - genetics Kinesin - metabolism microRNA MicroRNAs MicroRNAs - genetics MicroRNAs - metabolism MicroRNAs - physiology miR-1290 Nanog Homeobox Protein NF-kappa B - metabolism Phosphatase Proteins Proto-Oncogene Proteins c-akt - metabolism Proto-Oncogene Proteins c-myc - metabolism RNA Interference Studies Transcription factors Transcription, Genetic Up-Regulation Wnt Signaling Pathway
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!