Elevated C1rC1sC1inh levels independently predict atherosclerotic coronary heart disease

► Complement activation in ischaemic heart disease. ► Classical complement pathway is activated in coronary atherosclerosis. ► C1rC1sC1inh is a promising cardiovascular biomarker. Clinical studies as well as animal models emphasized the importance of the complement system in the pathogenesis of coro...

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Veröffentlicht in:	Molecular immunology 2013-05, Vol.54 (1), p.8-13
Hauptverfasser:	Horváth, Zsófia, Csuka, Dorottya, Vargova, Katarina, Kovács, Andrea, Molnár, Andrea Ágnes, Gulácsi-Bárdos, Petra, Leé, Sarolta, Varga, Lilian, Kiss, Róbert Gábor, Préda, István, Füst, George
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Atherosclerosis - blood Atherosclerosis - diagnosis Biomarker C1rC1sC1inh Case-Control Studies Classical pathway of complement activation Cohort Studies Complement Activation - physiology Complement C1 - analysis Complement C1 - metabolism Complement C1 Inactivator Proteins - analysis Complement C1 Inactivator Proteins - metabolism Complement C1r - analysis Complement C1r - metabolism Complement C1s - analysis Complement C1s - metabolism Complement system Coronary Artery Disease - blood Coronary Artery Disease - diagnosis Coronary heart disease Female Humans Male Middle Aged Prognosis Stable angina
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